{"id":"W2040575854","doi":"10.2174/156652309787354667","title":"A Possible Approach for Stem Cell Gene Therapy of Fanconi Anemia","year":2009,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Fanconi anemia; Genetic enhancement; Gene; Stem cell; Anemia; Medicine; Cancer research; Genetics; Biology; Computational biology; Bioinformatics; DNA repair; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001989747,0.0004347206,0.0002964168,0.0004550159,0.0003332718,0.000457166,0.0003572999,0.0007243979,0.002039994],"category_scores_gemma":[0.00008877132,0.0001387153,0.0004205756,0.0003114363,0.0003272846,0.0004239696,0.0003019362,0.0007915432,0.0006785888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003523177,"about_ca_system_score_gemma":0.0004250163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003841912,"about_ca_topic_score_gemma":0.0004803443,"domain_scores_codex":[0.9998865,0.00002128584,0.000005663245,0.00003059227,0.00003872145,0.00001716683],"domain_scores_gemma":[0.9999733,0.000005111063,0.000005776485,0.000003265772,0.000005730772,0.000006850868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001551944,0.0002717151,0.0003685488,0.001009546,0.00005617712,0.0007285082,0.0001536783,0.0008832843,0.8690338,0.03035338,0.003925079,0.09306121],"study_design_scores_gemma":[0.0001281632,0.001175355,0.001647791,0.0001672838,0.0001910316,0.003283824,0.00009268038,0.003444866,0.6898249,0.01188177,0.288108,0.00005435958],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.2231863,0.2226795,0.4664487,0.01026871,0.00318053,0.0006934615,0.0009153495,0.00182025,0.07080714],"genre_scores_gemma":[0.6904664,0.1353817,0.1324109,0.002679269,0.0004209739,0.0005586399,0.0009951741,0.0001537888,0.03693321],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002039994,"threshold_uncertainty_score":0.006824493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05281824577955205,"score_gpt":0.3684791430286231,"score_spread":0.315660897249071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}