{"id":"W2040575854","doi":"10.2174/156652309787354667","title":"A Possible Approach for Stem Cell Gene Therapy of Fanconi Anemia","year":2009,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Fanconi anemia; Genetic enhancement; Gene; Stem cell; Anemia; Medicine; Cancer research; Genetics; Biology; Computational biology; Bioinformatics; DNA repair; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002223778,0.0006142186,0.001130097,0.0001160649,0.0000574355,0.00002668323,0.0005484336,0.0004030461,0.000008166669],"category_scores_gemma":[0.00000240101,0.000507539,0.0008184789,0.0001726456,0.0000366751,0.00000237612,0.00004691599,0.0001885267,0.000002408185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002477262,"about_ca_system_score_gemma":0.0002514041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001167423,"about_ca_topic_score_gemma":2.029663e-7,"domain_scores_codex":[0.9980006,0.00007569137,0.0006227113,0.0006956179,0.0001679304,0.0004375111],"domain_scores_gemma":[0.9986351,0.00001771252,0.0003262884,0.0008035082,0.0001029474,0.0001144247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005143679,0.0002283961,0.000001997493,0.002249306,0.0001258827,3.034574e-7,0.00003879296,0.00007767337,0.02371338,0.000003521272,0.0008042541,0.9727051],"study_design_scores_gemma":[0.0009668639,0.0005386951,0.000002269984,0.0002648875,0.00007035021,0.00001194975,0.000006401373,0.00002243053,0.1469932,0.000006311082,0.8506043,0.0005123499],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001080294,0.9735256,0.02307139,0.000001954645,0.000410086,0.001589038,0.0001835114,0.00002253808,0.0001156219],"genre_scores_gemma":[0.000277845,0.9941744,0.002809336,0.00001867499,0.0007879208,0.0002888438,0.001287849,0.0001124857,0.000242618],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9721927,"threshold_uncertainty_score":0.9997376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05281824577955205,"score_gpt":0.3684791430286231,"score_spread":0.315660897249071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}