{"id":"W2040581421","doi":"10.1210/en.2004-0880","title":"Norepinephrine Induction of Mitogen-Activated Protein Kinase Phosphatase-1 Expression in Rat Pinealocytes: Distinct Roles of α- and β-Adrenergic Receptors","year":2004,"lang":"en","type":"article","venue":"Endocrinology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Pinealocyte; Internal medicine; Protein kinase A; Endocrinology; Receptor; Biology; Protein kinase C; Stimulation; Adrenergic receptor; Messenger RNA; Activator (genetics); Signal transduction; Kinase; Pineal gland; Cell biology; Medicine; Biochemistry; Melatonin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005762952,0.0001986943,0.0002916081,0.0001126223,0.00003087317,0.000003752778,0.0001565749,0.0001265998,0.00002183864],"category_scores_gemma":[0.0001819324,0.0001881194,0.00004647547,0.0001713414,0.0002504712,0.0000114969,0.00015918,0.0001144992,0.000001130239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002349006,"about_ca_system_score_gemma":0.00007067824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003540072,"about_ca_topic_score_gemma":0.0001910858,"domain_scores_codex":[0.9987682,0.00007605798,0.0003897796,0.000389698,0.00009673931,0.0002795581],"domain_scores_gemma":[0.9992818,0.00001084909,0.000234246,0.0003462548,0.00007035145,0.00005647296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005338518,0.0001474192,0.001830783,0.00006576561,0.00001967752,0.00001215862,0.00003549664,0.0001441121,0.9912418,0.0008529846,0.00007493095,0.005041011],"study_design_scores_gemma":[0.002203743,0.000569742,0.002513409,0.00009736945,0.000008814508,0.0000202147,0.0000485009,0.000001706476,0.9915465,0.0002268503,0.002599526,0.000163611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842789,0.01487593,0.0001633891,0.00006544052,0.0001269356,0.0003677591,0.00009359542,0.0000139533,0.00001406576],"genre_scores_gemma":[0.9975005,0.0003833948,0.00140325,0.00001563418,0.00005882712,0.00009038226,0.0004976396,0.00002077141,0.00002953596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01449254,"threshold_uncertainty_score":0.7671286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01012919981493339,"score_gpt":0.2423679170202809,"score_spread":0.2322387172053475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}