{"id":"W2040606511","doi":"10.1073/pnas.0706556104","title":"Control of transposase activity within a transpososome by the configuration of the flanking DNA segment of the transposon","year":2007,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institutes of Health","keywords":"Transposase; Tn10; Transposable element; DNA; Biology; Site-specific recombination; Cleavage (geology); Genetics; Chemistry; Recombinase; Recombination; Mutant; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003533451,0.0003329602,0.000183542,0.0001346658,0.00014247,0.0007463323,0.0003819104,0.0002361471,0.0007957394],"category_scores_gemma":[0.0007023166,0.0002994995,0.000103583,0.0001177811,0.0004464673,0.0002240125,0.0002421947,0.0003580965,0.0003230744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003920007,"about_ca_system_score_gemma":0.0002836477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003425969,"about_ca_topic_score_gemma":0.0006939099,"domain_scores_codex":[0.9996799,0.00008176635,0.00002034982,0.00009948568,0.0000732061,0.00004534421],"domain_scores_gemma":[0.9996432,0.000116527,0.00009450955,0.00004796861,0.00002847559,0.00006935593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003488687,0.000006453859,0.00009068549,0.000005789904,0.000001223047,0.00001329009,0.000009840687,0.00004728307,0.999348,0.0001314903,0.000003198117,0.0003078293],"study_design_scores_gemma":[0.000008293267,0.00008007479,0.0008235466,0.000001735637,0.000004756427,0.00006560762,0.00001501208,0.001084764,0.9975607,0.00003993342,0.000311902,0.000003649868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955491,0.000208372,0.003225034,0.0000270646,0.00001138801,0.00001350285,0.00003461047,0.00005007338,0.0008808268],"genre_scores_gemma":[0.9970099,0.0001191748,0.002181085,0.00001332333,0.000004003624,0.0000101415,0.00004528589,0.00002086802,0.0005961993],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007957394,"threshold_uncertainty_score":0.002844214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01485195502475617,"score_gpt":0.2803463066033597,"score_spread":0.2654943515786036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}