{"id":"W2040614951","doi":"10.1242/dev.051300","title":"The time to measure positional information: maternal Hunchback is required for the synchrony of the Bicoid transcriptional response at the onset of zygotic transcription","year":2010,"lang":"en","type":"article","venue":"Development","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Centre National de la Recherche Scientifique; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Infrastructures en Biologie Santé et Agronomie","keywords":"Drosophila embryogenesis; Biology; Morphogen; Gap gene; Mitosis; Genetics; Cell biology; Transcription factor; Drosophila melanogaster; Transcription (linguistics); Morphogenesis; Gene expression; Zygote; Embryo; Gene; Embryogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002732265,0.0002626512,0.0002108503,0.0003591604,0.0003522001,0.0007391939,0.000353448,0.0003497387,0.00190873],"category_scores_gemma":[0.0006236575,0.0002783328,0.0001271844,0.0002257921,0.0003594449,0.0005729658,0.0004904227,0.0006316418,0.00056897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009220528,"about_ca_system_score_gemma":0.0005490656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001802857,"about_ca_topic_score_gemma":0.003254209,"domain_scores_codex":[0.9997062,0.00002841307,0.00001885658,0.00009052994,0.000113403,0.00004253007],"domain_scores_gemma":[0.9995346,0.0001092673,0.0001335215,0.00004256131,0.00008301744,0.00009697821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005658206,0.000005805722,0.0005323964,0.00001893706,0.000001163722,0.00001594611,0.00001889043,0.00003427388,0.9978175,0.0001260406,0.00001065832,0.001361748],"study_design_scores_gemma":[0.000006297336,0.0001124009,0.02353725,0.000007881007,0.000007098946,0.0001020447,0.00006315942,0.001025024,0.974113,0.000130685,0.0008876773,0.000007537543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682708,0.002436577,0.0252,0.0001406032,0.00006371742,0.00005139063,0.0003719322,0.0002307258,0.003234365],"genre_scores_gemma":[0.9865434,0.0006519405,0.009007365,0.00006217416,0.00001098649,0.00005045708,0.0003455882,0.00006632079,0.003261932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00190873,"threshold_uncertainty_score":0.006690025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006710958814396579,"score_gpt":0.2117770739646751,"score_spread":0.2050661151502785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}