{"id":"W2040635272","doi":"10.1016/j.virol.2009.06.027","title":"Propensity for HBZ-SP1 isoform of HTLV-I to inhibit c-Jun activity correlates with sequestration of c-Jun into nuclear bodies rather than inhibition of its DNA-binding activity","year":2009,"lang":"en","type":"article","venue":"Virology","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Ligue Contre le Cancer; Centre National de la Recherche Scientifique; Association pour la Recherche sur le Cancer; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Psychological repression; c-jun; Mutant; Biology; Transcription factor; DNA; Zipper; Transcription (linguistics); bZIP domain; DNA-binding protein; DNA-binding domain; Binding site; Gene isoform; Leucine zipper; Binding domain; Molecular biology; Cell biology; Biochemistry; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002684703,0.000215086,0.0006645639,0.0001719209,0.0001809992,0.000003759811,0.00009677654,0.0003435341,0.00002766516],"category_scores_gemma":[0.00008565661,0.0001632127,0.0001024527,0.0001270976,0.0003852669,0.0001764525,0.00008230969,0.0002123745,0.00001888285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004077721,"about_ca_system_score_gemma":0.00004624112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001592564,"about_ca_topic_score_gemma":0.0003748562,"domain_scores_codex":[0.9988984,0.0001375519,0.0003099882,0.0003093578,0.00004920061,0.0002955283],"domain_scores_gemma":[0.9990612,0.0001184756,0.0004264973,0.00019242,0.0001803552,0.00002108013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003026383,0.0004004345,0.002278674,0.0001092566,0.0001662274,0.000001328648,0.002068667,0.00001305237,0.9877055,0.001149762,0.0001413195,0.00293934],"study_design_scores_gemma":[0.00122485,0.005088928,0.04981386,0.00007947915,0.00009110284,0.00001533477,0.0001808382,0.000009563679,0.9426136,0.0003971951,0.0003171849,0.0001680833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977335,0.0001284385,0.0004006505,0.0004593203,0.0001541856,0.000668831,0.00006148658,0.000035612,0.0003579499],"genre_scores_gemma":[0.9993749,0.00005343742,0.0001930497,0.00005912513,0.00001954067,0.00001680049,0.00001902629,0.0000152613,0.0002488502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04753518,"threshold_uncertainty_score":0.6655622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01672474628122357,"score_gpt":0.2332465431388255,"score_spread":0.216521796857602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}