{"id":"W2040635272","doi":"10.1016/j.virol.2009.06.027","title":"Propensity for HBZ-SP1 isoform of HTLV-I to inhibit c-Jun activity correlates with sequestration of c-Jun into nuclear bodies rather than inhibition of its DNA-binding activity","year":2009,"lang":"en","type":"article","venue":"Virology","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Ligue Contre le Cancer; Centre National de la Recherche Scientifique; Association pour la Recherche sur le Cancer; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Psychological repression; c-jun; Mutant; Biology; Transcription factor; DNA; Zipper; Transcription (linguistics); bZIP domain; DNA-binding protein; DNA-binding domain; Binding site; Gene isoform; Leucine zipper; Binding domain; Molecular biology; Cell biology; Biochemistry; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003599919,0.0002294949,0.0002780206,0.0001589762,0.0002007213,0.0002889762,0.0001966111,0.0002796758,0.001585517],"category_scores_gemma":[0.000261532,0.0001672431,0.0003404607,0.0001459679,0.0002564393,0.0002172207,0.0001410951,0.0006929279,0.0004260172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002279129,"about_ca_system_score_gemma":0.0002764888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008945841,"about_ca_topic_score_gemma":0.0005989242,"domain_scores_codex":[0.9998109,0.00004231971,0.00001576575,0.00003598168,0.00003237606,0.00006269258],"domain_scores_gemma":[0.9996516,0.0001273565,0.00004932754,0.00006108433,0.00004693581,0.00006370863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000133685,0.00005118727,0.0005004209,0.00001935606,0.00001152634,0.00004427326,0.00001383026,0.00007503069,0.9984483,0.0001084735,0.00002501446,0.0005688904],"study_design_scores_gemma":[0.0000103622,0.0005285462,0.005688794,0.000001576885,0.00001110712,0.0002919371,0.00002352759,0.0004738386,0.9924435,0.00003598356,0.0004883311,0.000002406214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953911,0.0006627708,0.002223077,0.00005972365,0.00002400313,0.00002789305,0.0001775925,0.00004036883,0.001393455],"genre_scores_gemma":[0.9975286,0.0001868617,0.0006949995,0.00004210397,0.00001443524,0.00002288806,0.0004689211,0.0000127596,0.001028495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001585517,"threshold_uncertainty_score":0.005304098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01672474628122357,"score_gpt":0.2332465431388255,"score_spread":0.216521796857602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}