{"id":"W2040700439","doi":"10.1523/jneurosci.3869-10.2011","title":"GluA2 (GluR2) Regulates Metabotropic Glutamate Receptor-Dependent Long-Term Depression through N-Cadherin-Dependent and Cofilin-Mediated Actin Reorganization","year":2011,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"National Key Research and Development Program of China; Canadian Institutes of Health Research","keywords":"Metabotropic glutamate receptor; Cofilin; AMPA receptor; Long-term depression; Cell biology; Metabotropic glutamate receptor 5; Neuroscience; Synaptic plasticity; Biology; Metabotropic glutamate receptor 1; NMDA receptor; Chemistry; Actin cytoskeleton; Receptor; Cytoskeleton; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007193184,0.0003601112,0.000153679,0.000129234,0.0002379098,0.0002983581,0.0001403803,0.0002639822,0.001006639],"category_scores_gemma":[0.00008620312,0.0001136502,0.0002039832,0.00007728335,0.0002067877,0.0002399388,0.0002711133,0.0003240278,0.0003323251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002825686,"about_ca_system_score_gemma":0.0001218817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005723597,"about_ca_topic_score_gemma":0.001460681,"domain_scores_codex":[0.9999123,0.00001480934,0.000006033883,0.00001692228,0.0000218921,0.00002804019],"domain_scores_gemma":[0.9999529,0.000003578971,0.00001696074,0.000003717547,0.000006351962,0.00001650348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006610596,0.00001470293,0.000255262,0.00001741805,0.00000449572,0.00007967652,0.000009450689,0.00004049954,0.9985808,0.00009540798,0.00004713575,0.0007890264],"study_design_scores_gemma":[0.00006800875,0.0003202754,0.06022232,0.00001235285,0.00005104844,0.0008751531,0.0001099803,0.004424402,0.9286517,0.0002282132,0.005022563,0.00001410256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949529,0.001401849,0.001520832,0.0001253461,0.00002456256,0.00001092384,0.00009414634,0.00006188027,0.001807626],"genre_scores_gemma":[0.9973626,0.0006279023,0.0004772711,0.00003406272,0.000009069235,0.00001330561,0.00008816881,0.000009518636,0.001378165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001006639,"threshold_uncertainty_score":0.003367543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07650962597664379,"score_gpt":0.3280389271528689,"score_spread":0.2515293011762251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}