{"id":"W2040716340","doi":"10.1074/jbc.m113.501007","title":"Regulation of the Src Kinase-associated Phosphoprotein 55 Homologue by the Protein Tyrosine Phosphatase PTP-PEST in the Control of Cell Motility","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Faculty of Medicine, McGill University; McGill University","keywords":"Cell biology; Biology; Protein tyrosine phosphatase; Phosphoprotein; Proto-oncogene tyrosine-protein kinase Src; Signal transducing adaptor protein; SH3 domain; Protein kinase domain; Phosphorylation; Mutant; Tyrosine phosphorylation; Adapter molecule crk; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001127033,0.0002297786,0.0003789234,0.00001135289,0.00008084527,0.0000217495,0.0009910406,0.0003280903,0.0001192037],"category_scores_gemma":[0.001351588,0.0001069956,0.0002649814,0.000226741,0.0005409906,0.00001260292,0.0001429025,0.0004154015,0.00000171741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003913475,"about_ca_system_score_gemma":0.0001022011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000157251,"about_ca_topic_score_gemma":0.000004885234,"domain_scores_codex":[0.9979928,0.0003421456,0.0008310163,0.0002338892,0.0003255176,0.0002746518],"domain_scores_gemma":[0.9977187,0.0001192213,0.001213254,0.0005606805,0.0003281212,0.00006001941],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002062612,0.0004506724,0.003820957,0.00003992987,0.00003614465,0.000002685312,0.00001684849,0.00003273363,0.9925354,0.00002178638,0.002418738,0.0004178418],"study_design_scores_gemma":[0.001243307,0.0002788386,0.03276667,0.00006464132,0.0000269378,0.00001940841,0.00008613862,0.00002689335,0.9645157,0.0004287124,0.0004342298,0.0001085081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865761,0.01115869,0.0001363704,0.000936046,0.00004090698,0.0007632111,0.0003210808,0.000003331995,0.00006421278],"genre_scores_gemma":[0.9992912,0.0000811364,0.0001041882,0.0002021405,0.00007038122,0.00006095531,0.0001056942,0.00001036242,0.00007392926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02894571,"threshold_uncertainty_score":0.4363154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008363628155932524,"score_gpt":0.2089760815650665,"score_spread":0.2006124534091339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}