{"id":"W2040741470","doi":"10.1163/156856202320176510","title":"Cytotoxic reaction and TNF-α response of macrophages to polyurethane particles","year":2002,"lang":"en","type":"article","venue":"Journal of Biomaterials Science Polymer Edition","topic":"Orthopaedic implants and arthroplasty","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Viability assay; Polyurethane; Biomaterial; Incubation; Macrophage; Materials science; In vitro; Incubation period; Particle size; Biophysics; Inflammatory response; Immunology; Chemistry; Nanotechnology; Biology; Composite material; Inflammation; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001112141,0.00008205351,0.0002297136,0.0003647087,0.00009157082,0.00003965503,0.00005606924,0.00003905374,0.0001768457],"category_scores_gemma":[0.0002512303,0.00005884478,0.00003953968,0.0002950616,0.0003374369,0.0003906694,0.00002411607,0.00002887784,0.0000106895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000297229,"about_ca_system_score_gemma":0.00005953541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009554837,"about_ca_topic_score_gemma":3.821245e-7,"domain_scores_codex":[0.9987233,0.00006567084,0.0004294163,0.0001204262,0.0004717071,0.0001894741],"domain_scores_gemma":[0.9991591,0.00005027162,0.0003266131,0.0001019739,0.0001348205,0.0002272054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009092642,0.00008591497,0.0005601416,0.00001780238,0.000007513744,0.00004372681,0.000303176,9.612202e-8,0.9896458,0.000008256368,0.0003691632,0.008049079],"study_design_scores_gemma":[0.0006333623,0.00110629,0.08033521,0.0001508292,0.00003188884,0.001856281,0.0001537081,0.00001226265,0.9155362,0.00001062172,0.0001194591,0.00005388845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963435,0.0003551721,0.00004340799,0.001916608,0.001208907,0.00008636208,0.00002129581,0.000008705159,0.00001602665],"genre_scores_gemma":[0.9988157,0.000101776,0.0003671595,0.0001556475,0.0005096364,0.000001021678,5.428067e-7,0.000005918992,0.00004264194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07977507,"threshold_uncertainty_score":0.239962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02022684457700427,"score_gpt":0.2810212217271161,"score_spread":0.2607943771501118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}