{"id":"W2040788830","doi":"10.1097/00007691-200004000-00007","title":"A Simple High-Performance Liquid Chromatography Assay for Simultaneous Measurement of Adenosine, Guanosine, and the Oxypurine Metabolites in Plasma","year":2000,"lang":"en","type":"article","venue":"Therapeutic Drug Monitoring","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chromatography; Chemistry; High-performance liquid chromatography; Hypoxanthine; Inosine; Detection limit; Xanthine; Adenosine; Uric acid; Analyte; Guanosine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001869853,0.001541498,0.001282825,0.001701282,0.0006589853,0.0007125519,0.001353349,0.002064768,0.001461272],"category_scores_gemma":[0.002031545,0.0006997082,0.0007160102,0.001316526,0.0008042073,0.000835466,0.0007314856,0.00183332,0.001828234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006053636,"about_ca_system_score_gemma":0.001304804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007942001,"about_ca_topic_score_gemma":0.002102733,"domain_scores_codex":[0.9960861,0.001184907,0.0002136364,0.0005875739,0.001794139,0.0001337522],"domain_scores_gemma":[0.9983408,0.0006088004,0.0002997752,0.0001357915,0.0004284016,0.0001863267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001519732,0.0002517716,0.001551797,0.0003879319,0.000107149,0.0001873263,0.00004697824,0.00022457,0.9647598,0.0002327992,0.0006866672,0.03141115],"study_design_scores_gemma":[0.0001915978,0.002681157,0.01956864,0.00009991687,0.0003243481,0.004995932,0.0000584234,0.01042176,0.9408028,0.0006209285,0.02008646,0.0001480402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1390709,0.03629022,0.8089643,0.0006766265,0.0009476081,0.002547474,0.001704402,0.004197387,0.005601153],"genre_scores_gemma":[0.3026314,0.01345311,0.6661509,0.001486152,0.0006539585,0.003919848,0.002182392,0.0001597467,0.009362538],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002064768,"threshold_uncertainty_score":0.009888887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271633697835796,"score_gpt":0.2542842659760621,"score_spread":0.2415679289977042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}