{"id":"W2040830391","doi":"10.1007/s12602-011-9067-6","title":"Cyclic Tritrpticin Analogs with Distinct Biological Activities","year":2011,"lang":"en","type":"article","venue":"Probiotics and Antimicrobial Proteins","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Peptide; Cathelicidin; Antimicrobial; Antimicrobial peptides; Chemistry; Lipid bilayer; Membrane; Biochemistry; Cyclic peptide; Bilayer; Biological activity; Amphiphile; Biophysics; Biology; Stereochemistry; Computational biology; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000168568,0.000410192,0.000528882,0.0001341095,0.000449866,0.00006678061,0.0002318304,0.0003106136,0.0002942848],"category_scores_gemma":[0.0000255945,0.0002905618,0.0001107956,0.0001620438,0.001170316,0.0002054688,0.0001837418,0.0004430293,0.00007723836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002263085,"about_ca_system_score_gemma":0.00005850363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002927183,"about_ca_topic_score_gemma":0.0001000907,"domain_scores_codex":[0.9983122,0.0001146206,0.0003369163,0.0005548749,0.00003502829,0.0006464006],"domain_scores_gemma":[0.9993919,0.00005259957,0.000186098,0.0002611734,0.00005282909,0.00005547428],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007769616,0.0005684368,0.006834939,0.000116977,0.0002291925,0.00003240461,0.0008201215,8.22909e-7,0.9839468,0.003228567,0.0008832671,0.002561518],"study_design_scores_gemma":[0.002359057,0.001894081,0.01547019,0.0002866078,0.0001195127,0.0005126584,0.0004917146,0.000003839625,0.9741219,0.0004059158,0.003371291,0.0009632611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941188,0.0002512783,0.001131208,0.0002031503,0.0001885393,0.0007477805,0.0001175108,0.0001777064,0.003064036],"genre_scores_gemma":[0.9952435,0.0001426089,0.002998089,0.0002290721,0.00005791836,0.00001682051,0.00005931383,0.00003964997,0.001212972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009824925,"threshold_uncertainty_score":0.9999546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02595750420378092,"score_gpt":0.2073036149570505,"score_spread":0.1813461107532696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}