{"id":"W2040833436","doi":"10.1126/science.1194006","title":"Regulating Direct-to-Consumer Personal Genome Testing","year":2010,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Health Economics","funders":"National Human Genome Research Institute","keywords":"Personal genomics; Genome; Computational biology; Genetic testing; Biology; Business; Genetics; Genomics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002859419,0.00006658176,0.00004561693,0.0000416967,0.0001487252,0.00003689497,0.000203035,0.00003036576,0.00001112512],"category_scores_gemma":[0.0004455307,0.00006433181,0.00001814138,0.0002511976,0.0001268815,0.000002896934,0.0001165392,0.00006683001,0.00001674049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004440305,"about_ca_system_score_gemma":0.00007227891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005977769,"about_ca_topic_score_gemma":0.00001420963,"domain_scores_codex":[0.9992689,0.000003147782,0.00007090402,0.0002854246,0.0001305006,0.0002411132],"domain_scores_gemma":[0.9996017,0.000008255846,0.00001531171,0.0001877188,0.00007130229,0.0001156702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000001164718,0.000003115927,0.003237189,0.000001910625,0.000001048651,3.506343e-7,0.00006579797,0.0001734219,0.9918566,0.000005837225,0.00001735833,0.004636201],"study_design_scores_gemma":[0.00008293641,0.00005191591,0.08803177,0.000005339222,0.000002838254,0.00002491583,0.0000412312,0.001647391,0.8925061,0.000009925213,0.01741335,0.0001823423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932283,0.00008697782,0.001304824,0.00004199781,0.0002403112,0.00005453122,0.000002276381,0.0000149724,0.005025832],"genre_scores_gemma":[0.9849274,0.000001075913,0.01438981,0.00008201497,0.0001769615,0.000004533299,0.000001467336,0.0000070908,0.0004096361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09935056,"threshold_uncertainty_score":0.2623375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00934836039390705,"score_gpt":0.2896105275370234,"score_spread":0.2802621671431163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}