{"id":"W2040833436","doi":"10.1126/science.1194006","title":"Regulating Direct-to-Consumer Personal Genome Testing","year":2010,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Health Economics","funders":"National Human Genome Research Institute","keywords":"Personal genomics; Genome; Computational biology; Genetic testing; Biology; Business; Genetics; Genomics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01796795,0.0005878992,0.0004600289,0.001081191,0.001081892,0.003693494,0.002475739,0.004533551,0.01892553],"category_scores_gemma":[0.02159154,0.0002937924,0.0007609932,0.0009915367,0.003647817,0.002848925,0.002719571,0.004255618,0.00510089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002122249,"about_ca_system_score_gemma":0.0048325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002872581,"about_ca_topic_score_gemma":0.003572471,"domain_scores_codex":[0.9794551,0.006093057,0.0008968141,0.001714463,0.01056437,0.001276186],"domain_scores_gemma":[0.9596295,0.02043631,0.003902653,0.004470563,0.01019676,0.001364272],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004727317,0.001726321,0.01652862,0.0009647057,0.0001037658,0.001242201,0.002715117,0.003289566,0.1713742,0.2474604,0.127784,0.4263384],"study_design_scores_gemma":[0.0002310917,0.0007772112,0.01317285,0.0005699461,0.00009276667,0.001860839,0.002066774,0.004905132,0.1198248,0.08490805,0.7714289,0.0001616539],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.0734723,0.008388767,0.302623,0.08921815,0.003848311,0.004354403,0.001049182,0.005062167,0.5119837],"genre_scores_gemma":[0.5725338,0.007719095,0.2157928,0.05507138,0.002018518,0.004174215,0.002306279,0.001503079,0.1388807],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01892553,"threshold_uncertainty_score":0.09502476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00934836039390705,"score_gpt":0.2896105275370234,"score_spread":0.2802621671431163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}