{"id":"W2040859555","doi":"10.1371/journal.pone.0078096","title":"Bridging the Gap between Single Molecule and Ensemble Methods for Measuring Lateral Dynamics in the Plasma Membrane","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Lundbeckfonden; LEO Pharma; H. Lundbeck A/S; Novo Nordisk Fonden; Novo Nordisk","keywords":"Membrane; Biophysics; Biotinylation; Molecule; Chemistry; Macromolecule; Lipid bilayer; Fluorescence correlation spectroscopy; Membrane protein; Dynamics (music); Microscopy; Biological system; Chemical physics; Materials science; Physics; Biochemistry; Biology; Optics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003831428,0.0001206219,0.000142591,0.00002698113,0.00009718641,0.00005604818,0.0002287362,0.00008462884,0.000001492022],"category_scores_gemma":[0.000149394,0.00008389276,0.00003281272,0.00006483214,0.00007869591,0.000009068956,0.0000966301,0.0001178255,0.000001053963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000273282,"about_ca_system_score_gemma":0.00001079902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003395102,"about_ca_topic_score_gemma":0.00003302276,"domain_scores_codex":[0.9991803,0.0001093482,0.0001533822,0.0002296369,0.00008503172,0.0002423522],"domain_scores_gemma":[0.9995164,0.00007556315,0.0000535278,0.0002717992,0.0000556148,0.00002712247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001125351,0.00006647185,0.001433877,0.00003246294,0.00003154893,2.683345e-7,0.0000824891,0.000002621779,0.9939885,0.0000387327,0.00002649978,0.004285238],"study_design_scores_gemma":[0.0001824859,0.0001169803,0.0004655076,0.00004622335,0.00002741216,0.000002659437,0.00005687751,0.003926646,0.9945269,0.0004816395,0.00005099078,0.0001157225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8780328,0.0002033898,0.120297,0.0005892407,0.000008433409,0.0006490948,0.00000977841,0.00001863638,0.0001915973],"genre_scores_gemma":[0.8092779,0.00004799938,0.1901363,0.0001735962,0.00007652461,0.0001540132,0.00003491087,0.00002387524,0.00007487099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06983931,"threshold_uncertainty_score":0.3421048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05175184243873827,"score_gpt":0.2991675473602592,"score_spread":0.2474157049215209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}