{"id":"W2040871017","doi":"10.1016/j.molcel.2006.07.035","title":"DNA Degradation at Unprotected Telomeres in Yeast Is Regulated by the CDK1 (Cdc28/Clb) Cell-Cycle Kinase","year":2006,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"National Cancer Institute","keywords":"Genome instability; Telomere; Biology; Cyclin-dependent kinase 1; Cell biology; Cell cycle; DNA re-replication; Saccharomyces cerevisiae; DNA repair; DNA damage; DNA; Genetics; Cell; Eukaryotic DNA replication; Yeast","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001541936,0.0004140538,0.000324309,0.0003947654,0.0003797086,0.0008919244,0.0002550718,0.0002316888,0.0009914699],"category_scores_gemma":[0.0002203806,0.0002537237,0.0002688991,0.0001958003,0.0003043103,0.0003605677,0.0003352226,0.0004817174,0.0006715556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007836138,"about_ca_system_score_gemma":0.0002751167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001558693,"about_ca_topic_score_gemma":0.001802198,"domain_scores_codex":[0.9999129,0.000008539336,0.000009591314,0.00002379113,0.00002232343,0.00002293594],"domain_scores_gemma":[0.999777,0.00002894163,0.00007957077,0.00002963683,0.00003248767,0.00005228551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005631068,0.00003661127,0.001158888,0.00006427892,0.000009473206,0.0001287522,0.00004166903,0.0002963442,0.9934111,0.0003062134,0.0001802054,0.003803402],"study_design_scores_gemma":[0.00003744086,0.0001398464,0.01523167,0.00001329425,0.00001728414,0.0004227296,0.00008340067,0.002861553,0.9782028,0.0003401483,0.002635106,0.00001486949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884143,0.00818684,0.001867272,0.0001273428,0.00003595695,0.000006836676,0.0003641006,0.0001943416,0.0008030253],"genre_scores_gemma":[0.9959521,0.001208104,0.0007843988,0.00003172462,0.000008108743,0.000005959247,0.0004858662,0.00004251247,0.001481219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001558693,"threshold_uncertainty_score":0.005685508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005081358839324048,"score_gpt":0.2010377006117716,"score_spread":0.1959563417724476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}