{"id":"W2040989154","doi":"10.1089/gte.2004.8.222","title":"Accuracy of Cancer Family Histories: Comparison of Two Breast Cancer Syndromes","year":2004,"lang":"en","type":"article","venue":"Genetic Testing","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cancer Care Ontario","funders":"National Human Genome Research Institute; National Institutes of Health","keywords":"Medicine; Family history; Cancer; Medical diagnosis; Breast cancer; Cohort; Ovarian cancer; Genetic testing; Li–Fraumeni syndrome; Oncology; Internal medicine; Pathology; Genetics; Biology; Gene; Germline mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000719397,0.0001575754,0.0002481717,0.0000506205,0.00006067588,0.000007222224,0.0002446815,0.00007968531,0.00002949942],"category_scores_gemma":[0.0001395911,0.0001651447,0.0000628671,0.0002497204,0.0001601048,0.000003685262,0.00009745634,0.00007470846,0.000001185032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000155146,"about_ca_system_score_gemma":0.0008666149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002846367,"about_ca_topic_score_gemma":0.0004486316,"domain_scores_codex":[0.9988359,0.00002396699,0.000428097,0.000304355,0.0001835416,0.0002241862],"domain_scores_gemma":[0.9988388,0.00004210111,0.0003795117,0.0003501118,0.0003361811,0.00005332862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001731486,0.00005987792,0.1684595,0.00008937863,0.00007810414,9.518945e-7,0.0004021756,0.06055798,0.7224988,0.00001533453,0.0002326094,0.04758804],"study_design_scores_gemma":[0.001864467,0.0002776524,0.3281958,0.0003369516,0.0001778815,0.0000488318,0.0005597761,0.0004286666,0.6644701,0.0002847002,0.002852625,0.0005024598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9799734,0.01766904,0.001262925,0.0001229537,0.000367602,0.0001577199,0.0001374242,0.00001426404,0.0002946701],"genre_scores_gemma":[0.9814167,0.0001861092,0.0179824,0.00006315911,0.0001958616,0.00006564393,0.00001147912,0.00002989623,0.0000487245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1597364,"threshold_uncertainty_score":0.6734407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03931974102562871,"score_gpt":0.3476887180211113,"score_spread":0.3083689769954826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}