{"id":"W2041003815","doi":"10.1021/bc900443a","title":"Evaluation of Bifunctional Chelates for the Development of Gallium-Based Radiopharmaceuticals","year":2010,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Heart Institute; Nordion (Canada)","funders":"","keywords":"Chemistry; In vivo; DOTA; Yield (engineering); Radiochemistry; Chelation; Bifunctional; Nuclear chemistry; Combinatorial chemistry; Biochemistry; Inorganic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005927981,0.000485571,0.0003198305,0.0003502503,0.0001690607,0.0003406936,0.0002979585,0.0004891817,0.0004509285],"category_scores_gemma":[0.0006288211,0.0001416987,0.0001821315,0.0002249712,0.0002276464,0.000250692,0.0002644894,0.0002913303,0.0002452249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004850511,"about_ca_system_score_gemma":0.0002797292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009786591,"about_ca_topic_score_gemma":0.00137491,"domain_scores_codex":[0.999675,0.00008182375,0.00002369102,0.00006381478,0.000104835,0.00005072269],"domain_scores_gemma":[0.9996965,0.000060479,0.00005484658,0.0000277796,0.0001111191,0.00004943106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001312888,0.00001663452,0.00006302227,0.00006425646,0.000006359448,0.00002044779,0.00001021237,0.0001871544,0.9977191,0.00006038661,0.00002388814,0.0016972],"study_design_scores_gemma":[0.00001714123,0.0003576634,0.0004648082,0.000007098251,0.0000194991,0.00007382052,0.00000818238,0.0006416127,0.9959021,0.00001447724,0.002488839,0.000004854524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830873,0.004824274,0.009799158,0.0001180635,0.00003920278,0.0001782133,0.0003156496,0.00009613548,0.001541917],"genre_scores_gemma":[0.9719455,0.003533155,0.02108847,0.0000879323,0.00001659156,0.0001825316,0.0007214544,0.00006421777,0.002360125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009786591,"threshold_uncertainty_score":0.003519297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09109159080330716,"score_gpt":0.3889071176233633,"score_spread":0.2978155268200561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}