{"id":"W2041003815","doi":"10.1021/bc900443a","title":"Evaluation of Bifunctional Chelates for the Development of Gallium-Based Radiopharmaceuticals","year":2010,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Heart Institute; Nordion (Canada)","funders":"","keywords":"Chemistry; In vivo; DOTA; Yield (engineering); Radiochemistry; Chelation; Bifunctional; Nuclear chemistry; Combinatorial chemistry; Biochemistry; Inorganic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00120264,0.0001202457,0.0001822262,0.00001288679,0.00008970166,0.00000510795,0.0001300036,0.0001273102,0.0009971058],"category_scores_gemma":[0.0003878508,0.00008798425,0.0001180637,0.0001201204,0.0002653375,0.00001683669,0.00001483547,0.0001971863,0.000003799159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003912362,"about_ca_system_score_gemma":0.0006335576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":5.415159e-7,"about_ca_topic_score_gemma":1.707186e-7,"domain_scores_codex":[0.9987788,0.00001006012,0.0004093811,0.0001932366,0.0004632265,0.0001453601],"domain_scores_gemma":[0.9985582,0.0002799215,0.0001447481,0.0002804736,0.0006254022,0.0001112691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000126592,0.0002034314,0.0002042307,0.0004028498,0.0001232663,7.952617e-8,0.00002523357,0.00004017514,0.9942579,0.00005230867,0.0001261471,0.004437731],"study_design_scores_gemma":[0.001929435,0.00001040064,0.001214422,0.00003249929,0.0005172044,0.000005973493,0.00002996602,0.01192011,0.9742841,0.0001228458,0.009847756,0.00008533319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945946,0.0003520725,0.001338952,0.0009786608,0.00007071657,0.0007051166,0.00004143227,0.00002402721,0.001894474],"genre_scores_gemma":[0.9941797,0.000005540287,0.005029687,0.00006356127,0.0001717536,0.0003386779,0.0000792518,0.00001261293,0.0001192641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01997391,"threshold_uncertainty_score":0.9999161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09109159080330716,"score_gpt":0.3889071176233633,"score_spread":0.2978155268200561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}