{"id":"W2041049413","doi":"10.1021/ol701797e","title":"First Total Synthesis and Structural Reassignment of (−)-Aplysiallene","year":2007,"lang":"en","type":"article","venue":"Organic Letters","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Total synthesis; Core (optical fiber); Key (lock); Combinatorial chemistry; Stereochemistry; Oxidative phosphorylation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001878144,0.0003970876,0.0002931925,0.0002389795,0.0003930383,0.0002645328,0.0004184405,0.0002469285,0.003577602],"category_scores_gemma":[0.0002676645,0.000171204,0.0003125389,0.0003340142,0.0002812425,0.000452547,0.0005149671,0.0007347489,0.001091848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003497187,"about_ca_system_score_gemma":0.0005642548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001095829,"about_ca_topic_score_gemma":0.001200497,"domain_scores_codex":[0.9998733,0.00001506133,0.00001311779,0.00002884128,0.00002737153,0.00004222277],"domain_scores_gemma":[0.9998819,0.00001184138,0.00001571594,0.00003535177,0.00002576462,0.00002949849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001511768,0.00005228599,0.0001328352,0.0002342268,0.00002521792,0.0004538963,0.0003108684,0.0008848844,0.9670429,0.003559759,0.0005453502,0.02660655],"study_design_scores_gemma":[0.00004031271,0.0009045478,0.001218802,0.00001902718,0.00003281432,0.0007068132,0.00009779752,0.0004404468,0.9512451,0.001046297,0.04419924,0.00004891035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9058186,0.002927146,0.06224957,0.0003534612,0.0002872783,0.0003957686,0.002672112,0.0005529691,0.02474312],"genre_scores_gemma":[0.9512349,0.002762012,0.02778892,0.0001681862,0.00003366416,0.0001463072,0.001851924,0.0001231327,0.01589101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003577602,"threshold_uncertainty_score":0.01196826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004910699628608762,"score_gpt":0.1980350782349602,"score_spread":0.1931243786063514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}