{"id":"W2041049413","doi":"10.1021/ol701797e","title":"First Total Synthesis and Structural Reassignment of (−)-Aplysiallene","year":2007,"lang":"en","type":"article","venue":"Organic Letters","topic":"Traditional and Medicinal Uses of Annonaceae","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Total synthesis; Core (optical fiber); Key (lock); Combinatorial chemistry; Stereochemistry; Oxidative phosphorylation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008194591,0.0000757827,0.00008430673,0.00002032026,0.00003585201,0.000003268772,0.00005616379,0.00004108571,0.00005439277],"category_scores_gemma":[0.00003241792,0.00006468174,0.00003223281,0.00002873907,0.00008289499,0.000002287503,0.00002960689,0.00003348121,0.00000193891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000105543,"about_ca_system_score_gemma":0.00001276725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001216784,"about_ca_topic_score_gemma":0.0000174916,"domain_scores_codex":[0.9995109,0.000007142179,0.000112903,0.0001418111,0.0001031195,0.0001241441],"domain_scores_gemma":[0.9997594,0.00002148283,0.00004113247,0.0001015399,0.00001443004,0.00006198453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006080993,0.00001102051,0.000852972,0.00001652358,0.00004030428,0.000006854934,0.00003430678,0.000003457941,0.9969212,0.00006257537,0.001067626,0.0009223815],"study_design_scores_gemma":[0.0003429333,0.0001446882,0.1095163,0.0000227937,0.00003275348,0.0000955639,0.00007956473,0.000003079708,0.8869819,0.00002460962,0.002625637,0.0001302169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968157,0.0001988184,0.0005770705,0.002179497,0.00007740819,0.0000445145,0.000009145879,0.000004372186,0.00009342481],"genre_scores_gemma":[0.9986948,0.00004733902,0.0004056276,0.0005822761,0.0002120637,0.000001352822,0.00001590397,0.00000870762,0.00003190587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1099393,"threshold_uncertainty_score":0.2637644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004910699628608762,"score_gpt":0.1980350782349602,"score_spread":0.1931243786063514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}