{"id":"W2041050215","doi":"10.1007/s00223-015-9994-4","title":"Deletion of Filamin A in Monocytes Protects Cortical and Trabecular Bone from Post-menopausal Changes in Bone Microarchitecture","year":2015,"lang":"en","type":"article","venue":"Calcified Tissue International","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research; Ontario Council on Graduate Studies, Council of Ontario Universities","keywords":"FLNA; Filamin; Osteoclast; Osteoporosis; Ovariectomized rat; X-ray microtomography; In vivo; Bone mineral; Densitometry; Medicine; Internal medicine; Endocrinology; Anatomy; Chemistry; Estrogen; Biology; Receptor; Cell; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001099741,0.0001082408,0.0001589084,0.0001015757,0.000008640443,0.0000130796,0.00008907677,0.0001148538,0.00002009139],"category_scores_gemma":[0.0002411854,0.0001061965,0.00001625309,0.00005523479,0.00008033554,0.000005114588,0.00007692244,0.00009109011,0.000002053851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001435359,"about_ca_system_score_gemma":0.0000509259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000380477,"about_ca_topic_score_gemma":0.0006661309,"domain_scores_codex":[0.9992274,0.00006129403,0.0001942747,0.0002480629,0.000140979,0.0001279999],"domain_scores_gemma":[0.9996578,0.00001632081,0.00005553097,0.0001127193,0.00007919531,0.00007841524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004592945,0.0001271913,0.002223245,0.00001071694,0.00001687796,0.00004021696,0.000211918,0.00002984136,0.9895334,0.0001347527,0.00009845039,0.007114125],"study_design_scores_gemma":[0.002786173,0.0003922789,0.08474725,0.00006372498,0.00001798857,0.00003313651,0.0002390083,0.000195404,0.9026808,0.0008190401,0.00778835,0.00023685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932611,0.005211683,0.0003913944,0.0005841452,0.00009505411,0.00020148,0.000156636,0.000004962384,0.00009354496],"genre_scores_gemma":[0.998264,0.00006991369,0.0008995429,0.0001226789,0.0001306542,0.00003905011,0.0003880676,0.00001069531,0.00007541304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08685258,"threshold_uncertainty_score":0.4330566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0135755486814095,"score_gpt":0.2637248753477145,"score_spread":0.2501493266663051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}