{"id":"W2041070854","doi":"10.1016/j.bbrc.2005.01.068","title":"Contribution of simple saccharides to the stabilization of amyloid structure","year":2005,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"Canadian Institutes of Health Research; Scottish Rite Charitable Foundation of Canada","keywords":"Fibrillogenesis; Chemistry; Hydrogen bond; Circular dichroism; Amyloid (mycology); Protein folding; Biophysics; Small molecule; Biochemistry; Molecule; Fibril; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002189989,0.00006815316,0.0001049936,0.00003244407,0.0001213753,0.00001090474,0.0004925977,0.0000894755,0.00000550798],"category_scores_gemma":[0.0006097208,0.00004643733,0.00004129502,0.0002575095,0.0004809976,0.000004274665,0.0004450517,0.0001448568,0.000001107016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001187737,"about_ca_system_score_gemma":0.00004872346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003751105,"about_ca_topic_score_gemma":0.00006587228,"domain_scores_codex":[0.9992075,0.0001095808,0.000181365,0.0001502405,0.0002006497,0.0001506722],"domain_scores_gemma":[0.9985867,0.00009457517,0.00004740244,0.0007296443,0.0004706724,0.00007097704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005125671,0.00005857272,0.0001811554,0.00001013845,0.00001257035,9.93189e-9,0.00003657162,0.000008667796,0.989614,0.005789076,0.0004902849,0.003747748],"study_design_scores_gemma":[0.0001353748,0.0001496473,0.001794929,0.000009624975,0.000006953317,7.439886e-7,0.00004091364,0.0005512897,0.9834621,0.001966791,0.011823,0.00005862901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951113,0.0007955781,0.0009183064,0.0026827,0.000005893739,0.0002784509,0.0001424867,0.000003527317,0.00006170648],"genre_scores_gemma":[0.9978126,0.000303286,0.001464514,0.00006453902,0.0000880359,0.00001823995,0.0002301204,0.0000051909,0.00001348126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01133271,"threshold_uncertainty_score":0.189366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02479887811626615,"score_gpt":0.3444002348993071,"score_spread":0.319601356783041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}