{"id":"W2041085893","doi":"10.1016/j.mito.2011.06.007","title":"Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes","year":2011,"lang":"en","type":"review","venue":"Mitochondrion","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Juvenile Diabetes Research Foundation United States of America","keywords":"Neurodegeneration; AMPK; Diabetes mellitus; Diabetic neuropathy; Mitochondrion; Endocrinology; Internal medicine; Mitochondrial biogenesis; Biology; Medicine; Neuroscience; Cell biology; Protein kinase A; Kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000576589,0.001144793,0.002148834,0.001873331,0.0002991554,0.001149079,0.001023708,0.001527798,0.002133625],"category_scores_gemma":[0.0006487519,0.0003295804,0.000464391,0.002339636,0.0006554808,0.001516699,0.0009479649,0.001854384,0.00153956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006283185,"about_ca_system_score_gemma":0.0008590099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001326944,"about_ca_topic_score_gemma":0.002814466,"domain_scores_codex":[0.9998472,0.0000196239,0.0000361873,0.00003094146,0.00005306472,0.00001297678],"domain_scores_gemma":[0.9996874,0.0001255382,0.00005837394,0.00001009488,0.00009181698,0.0000268004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001635436,0.00007921495,0.0003253802,0.01312475,0.0001607158,0.0004750852,0.00004201301,0.0002648294,0.002316789,0.002069631,0.02517871,0.9557993],"study_design_scores_gemma":[0.0000745153,0.0001480477,0.003147894,0.00595167,0.0005668369,0.005282681,0.0001511641,0.0002131684,0.001309607,0.005528242,0.9775686,0.00005769771],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000932827,0.9990572,0.0001375868,0.0002106037,0.0001662995,0.000002060773,0.00001490277,0.000004947028,0.0003131018],"genre_scores_gemma":[0.000533528,0.998489,0.0002159741,0.0001467804,0.0002459748,0.00000388074,0.00002512278,8.912687e-7,0.0003387129],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002148834,"threshold_uncertainty_score":0.007137716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03480939645409514,"score_gpt":0.2939151589732562,"score_spread":0.2591057625191611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}