{"id":"W2041103595","doi":"10.1016/j.tox.2008.05.011","title":"Methylmercury increases N-methyl-d-aspartate receptors on human SH-SY 5Y neuroblastoma cells leading to neurotoxicity","year":2008,"lang":"en","type":"article","venue":"Toxicology","topic":"Mercury impact and mitigation studies","field":"Environmental Science","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Northern British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neurotoxicity; NMDA receptor; Dizocilpine; Chemistry; Pharmacology; Memantine; Programmed cell death; Toxicity; Receptor; Neurotoxin; Apoptosis; Glutamate receptor; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002128027,0.0003472831,0.0004632408,0.0002356988,0.0003947199,0.0003037638,0.0002934585,0.0005463783,0.004602065],"category_scores_gemma":[0.000264188,0.0003152607,0.0007621079,0.0002779109,0.0002279531,0.0002886326,0.0002482528,0.0009114332,0.001201362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006614068,"about_ca_system_score_gemma":0.0004567566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01143181,"about_ca_topic_score_gemma":0.01784356,"domain_scores_codex":[0.9996923,0.00004425522,0.00003503083,0.00003925899,0.00008229032,0.0001067523],"domain_scores_gemma":[0.9998573,0.00004339379,0.00001665396,0.00002720579,0.0000371826,0.00001816906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000731245,0.00007414044,0.0006653958,0.00005310522,0.00002922123,0.0001568676,0.00007476171,0.00004247478,0.9969347,0.00005042263,0.0001879281,0.0009997389],"study_design_scores_gemma":[0.00005466486,0.001109988,0.01850579,0.000008814009,0.00006797989,0.0003759127,0.0002114985,0.0003636487,0.977791,0.0000404335,0.001460976,0.000009275684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956294,0.00138902,0.0004384614,0.0001933585,0.00007169573,0.00001593098,0.0003921866,0.00003805107,0.001831837],"genre_scores_gemma":[0.9893295,0.001737872,0.0005359997,0.00009851162,0.00001721743,0.00003419298,0.0008178743,0.00001183367,0.007416985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01143181,"threshold_uncertainty_score":0.02273053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05539101097982825,"score_gpt":0.3148892793291367,"score_spread":0.2594982683493084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}