{"id":"W2041134529","doi":"10.1242/dev.02011","title":"A <i>Gja1</i> missense mutation in a mouse model of oculodentodigital dysplasia","year":2005,"lang":"en","type":"article","venue":"Development","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":235,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Heart and Stroke Foundation; Hospital for Sick Children; Western University; Canada Research Chairs; University of Toronto; University of New Brunswick; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Missense mutation; Mutant; Mutation; Genetics; Connexin; Craniofacial; Mutant protein; Cell biology; Gene; Gap junction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003978594,0.001137047,0.0005460105,0.001502511,0.0005966011,0.0005074612,0.0005224352,0.001387513,0.003068856],"category_scores_gemma":[0.0002555336,0.0005271763,0.0004987474,0.0003647828,0.0009674794,0.0004055893,0.0005327435,0.00127742,0.001057334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005178284,"about_ca_system_score_gemma":0.0004045973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001110128,"about_ca_topic_score_gemma":0.001243129,"domain_scores_codex":[0.9995565,0.0000916066,0.0000638776,0.0001129098,0.00009911366,0.00007598894],"domain_scores_gemma":[0.9996338,0.00006277007,0.000109531,0.00003716366,0.00002339271,0.0001333861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003499356,0.0002450485,0.0002822118,0.00006061321,0.00001956858,0.001064893,0.00005039111,0.000180925,0.9946879,0.001068537,0.0003295036,0.001660488],"study_design_scores_gemma":[0.0005770096,0.00178453,0.007161236,0.0001097911,0.0001707357,0.008083952,0.0001640963,0.003989435,0.9634831,0.0008185615,0.01361691,0.00004050436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853864,0.001105503,0.005112531,0.0007765008,0.0002220479,0.0001548283,0.001180777,0.0006712566,0.005390267],"genre_scores_gemma":[0.9777853,0.001818854,0.007426512,0.0003212112,0.00007016188,0.000311502,0.00122309,0.0002242955,0.01081898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003068856,"threshold_uncertainty_score":0.01026636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116025109407563,"score_gpt":0.2306831652311793,"score_spread":0.2195229141371037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}