{"id":"W2041134529","doi":"10.1242/dev.02011","title":"A <i>Gja1</i> missense mutation in a mouse model of oculodentodigital dysplasia","year":2005,"lang":"en","type":"article","venue":"Development","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":235,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Heart and Stroke Foundation; Hospital for Sick Children; Western University; Canada Research Chairs; University of Toronto; University of New Brunswick; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Biology; Missense mutation; Mutant; Mutation; Genetics; Connexin; Craniofacial; Mutant protein; Cell biology; Gene; Gap junction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001083425,0.00009477882,0.0001259085,0.00005553168,0.00001613202,0.000005720497,0.00007337682,0.0000853577,0.000008840769],"category_scores_gemma":[0.00002276658,0.00008931159,0.00003536054,0.0000394113,0.00002534767,0.000002917673,0.00004943369,0.0000369577,0.000009329943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002279543,"about_ca_system_score_gemma":0.0001282819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005983717,"about_ca_topic_score_gemma":0.0002463119,"domain_scores_codex":[0.9993206,0.00001506526,0.0002570845,0.0001887744,0.00006873462,0.0001498033],"domain_scores_gemma":[0.9997427,0.000004337569,0.00005654072,0.0001197515,0.00004130388,0.00003540895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001931465,0.0001713286,0.001530352,0.00001618083,0.00003940678,0.000005364054,0.0007370559,0.003271201,0.9702659,0.0001342452,0.0003508686,0.02328494],"study_design_scores_gemma":[0.001225567,0.00007764819,0.00149137,0.00001145462,0.000003879001,0.00001996135,0.00009770759,0.002731051,0.9748875,0.00002279784,0.01921479,0.0002163057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972609,0.0001095481,0.00123453,0.00009547378,0.00001858018,0.0001108078,0.000008295155,0.000005405682,0.001156467],"genre_scores_gemma":[0.9914874,0.00002743954,0.006610136,0.0001737449,0.00002555174,0.00001942423,0.00008869556,0.000008439379,0.001559195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02306864,"threshold_uncertainty_score":0.3642021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01116025109407563,"score_gpt":0.2306831652311793,"score_spread":0.2195229141371037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}