{"id":"W2041189307","doi":"10.1038/gt.2011.142","title":"Gene therapy for retinal ganglion cell neuroprotection in glaucoma","year":2011,"lang":"en","type":"review","venue":"Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Glaucoma; Neuroprotection; Retinal ganglion cell; Optic nerve; Neuroscience; Retina; Intraocular pressure; Ophthalmology; Biology; Retinal; Blindness; Retinal degeneration; Medicine; Optometry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005868017,0.001046808,0.001457046,0.001636451,0.0002436281,0.0007384493,0.0009326609,0.001172743,0.002328638],"category_scores_gemma":[0.000510148,0.0002948559,0.0004317883,0.001436693,0.0006189036,0.0009955519,0.000482055,0.002208078,0.001591527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005974806,"about_ca_system_score_gemma":0.0006687823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001110958,"about_ca_topic_score_gemma":0.002640245,"domain_scores_codex":[0.9998831,0.00001719676,0.00001791314,0.00002048161,0.00004784345,0.0000136336],"domain_scores_gemma":[0.9998168,0.00009655372,0.00002229187,0.000006650589,0.00004153033,0.00001618651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001397931,0.0001385559,0.0001186735,0.008692893,0.00009266297,0.0004499565,0.00005290755,0.0005931447,0.008367674,0.004960239,0.03856705,0.9378263],"study_design_scores_gemma":[0.00007822465,0.0001267462,0.0006013953,0.001568673,0.0001589298,0.00194078,0.00004497259,0.0001925818,0.002670521,0.002552953,0.9900358,0.00002836781],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002471393,0.9969271,0.0006181736,0.0002706282,0.0003830489,0.000008488088,0.00002349771,0.0000138447,0.001508079],"genre_scores_gemma":[0.001312985,0.9959732,0.0007068061,0.0002402891,0.000226679,0.00001451052,0.0000455363,0.000004209714,0.001475846],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002328638,"threshold_uncertainty_score":0.007790029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03100403014773893,"score_gpt":0.2801954738643956,"score_spread":0.2491914437166567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}