{"id":"W2041253676","doi":"10.1126/scisignal.2005242","title":"Store-Operated Calcium Entry Promotes the Degradation of the Transcription Factor Sp4 in Resting Neurons","year":2014,"lang":"en","type":"article","venue":"Science Signaling","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Transcription factor; Degradation (telecommunications); Cell biology; Calcium; Calcium signaling; Transcription (linguistics); Chemistry; Neuroscience; Biology; Signal transduction; Computer science; Biochemistry; Gene; Telecommunications","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000874272,0.00008906209,0.0000850649,0.00009272897,0.0005519508,0.00008212057,0.0005339765,0.00003142565,0.00002016804],"category_scores_gemma":[0.001275571,0.00004661856,0.00004011417,0.001213917,0.0005353401,0.0002911226,0.00004699099,0.0001964913,0.000003267367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003696595,"about_ca_system_score_gemma":0.0001074468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008196972,"about_ca_topic_score_gemma":0.00001461014,"domain_scores_codex":[0.9984609,0.0002578444,0.0002246291,0.0003006773,0.0004850145,0.0002708635],"domain_scores_gemma":[0.9994485,0.000186829,0.0001125642,0.0001549961,0.00005819446,0.00003892611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00000334181,0.00001639777,0.0006204204,0.000005573116,1.638418e-7,1.501197e-7,0.001106856,0.002723374,0.9940037,0.0003635896,0.000002782611,0.00115366],"study_design_scores_gemma":[0.0001018752,0.0000309317,0.001992362,0.00005408815,0.000001963,0.000002326014,0.0002133852,0.03861636,0.9587851,0.00009793205,0.00004118156,0.00006248942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997033,0.000008342427,0.0009006058,0.0007191677,0.000870533,0.0002423856,0.000002725195,0.0000226461,0.0002006225],"genre_scores_gemma":[0.9996206,0.000002244484,0.00004434127,0.0001365646,0.00005322132,0.000005126827,2.49288e-7,0.000006486188,0.0001311631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03589299,"threshold_uncertainty_score":0.4245215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05760749544706129,"score_gpt":0.2795814928582656,"score_spread":0.2219739974112043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}