{"id":"W2041313070","doi":"10.1016/s1535-6108(03)00136-3","title":"Escape from Cbl-mediated downregulation","year":2003,"lang":"en","type":"article","venue":"Cancer Cell","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":234,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Receptor tyrosine kinase; Endocytosis; Downregulation and upregulation; Ubiquitin; Cell biology; Biology; Receptor; Lysosome; Signal transduction; Cancer research; Genetics; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002684734,0.0003499179,0.0003554432,0.0003185148,0.00027248,0.001204246,0.0004220848,0.0003975402,0.004704555],"category_scores_gemma":[0.0003505723,0.0001543671,0.0003733145,0.0001850009,0.0003116629,0.0003680307,0.0005813866,0.001575507,0.001922372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007377273,"about_ca_system_score_gemma":0.0003912197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008332485,"about_ca_topic_score_gemma":0.001217271,"domain_scores_codex":[0.999711,0.000029435,0.00001479807,0.00003824606,0.00008522005,0.0001212811],"domain_scores_gemma":[0.9997959,0.00004731328,0.00002398162,0.00006206191,0.00003616557,0.00003470426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001097392,0.00004780859,0.0005178783,0.00003999997,0.00001090149,0.0002075592,0.00003302131,0.00007063934,0.9886118,0.00239574,0.0006829846,0.007271901],"study_design_scores_gemma":[0.00004354968,0.0001777211,0.00822185,0.0000163104,0.00001794904,0.001446606,0.00008035889,0.00093158,0.9700347,0.0006371104,0.01838377,0.000008533377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9568055,0.004230976,0.008120816,0.001226377,0.0001910493,0.00006139348,0.001074333,0.0008218497,0.02746767],"genre_scores_gemma":[0.9852043,0.000459987,0.001083976,0.0002481768,0.00002363662,0.00003052241,0.0006208241,0.00007105993,0.01225746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004704555,"threshold_uncertainty_score":0.01573831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01826539337311441,"score_gpt":0.2899037747678703,"score_spread":0.2716383813947559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}