{"id":"W2041346792","doi":"10.1002/bit.20947","title":"Retroviral vector production using suspension‐adapted 293GPG cells in a 3L acoustic filter‐based perfusion bioreactor","year":2006,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; National Research Council Canada; Biotechnology Research Institute","funders":"","keywords":"Retrovirus; Cell culture; Viral vector; Vesicular stomatitis virus; Bioreactor; Biology; Transfection; Virology; Titer; Virus; Murine leukemia virus; Molecular biology; Recombinant DNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009198551,0.0008229924,0.001182631,0.0005673949,0.0004353276,0.0008420071,0.001166321,0.0009294213,0.001501962],"category_scores_gemma":[0.0003479497,0.0004298331,0.0008018536,0.0005394472,0.0003901346,0.0004122727,0.0007299842,0.002014253,0.002958011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004697891,"about_ca_system_score_gemma":0.0003842983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006651084,"about_ca_topic_score_gemma":0.0007707348,"domain_scores_codex":[0.9992527,0.0001312308,0.00008230562,0.0002000955,0.000243954,0.00008961865],"domain_scores_gemma":[0.9997496,0.00007592083,0.00005132908,0.00004535074,0.0000396814,0.00003807809],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000020753,0.00003068441,0.00005780192,0.00003077461,0.000003155106,0.00005841093,0.00002724967,0.00006664252,0.9986622,0.00006590167,0.00005523995,0.0009211638],"study_design_scores_gemma":[0.00002444622,0.0003298548,0.0009520841,0.00001819163,0.00002910343,0.0003423834,0.00002296589,0.002380109,0.9891805,0.00007867209,0.006623522,0.00001811786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.631357,0.002240425,0.3434687,0.0003665574,0.0004601202,0.002883936,0.00546099,0.00323956,0.01052285],"genre_scores_gemma":[0.595502,0.00376128,0.3605157,0.0004789629,0.0001763954,0.002655033,0.01397372,0.0008680998,0.02206874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001501962,"threshold_uncertainty_score":0.005024493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01209093925035836,"score_gpt":0.2353116813313803,"score_spread":0.2232207420810219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}