{"id":"W2041466580","doi":"10.1097/qad.0b013e3282f21b9d","title":"Efficacy and tolerability of long-term efavirenz plus nucleoside reverse transcriptase inhibitors for HIV-1 infection","year":2008,"lang":"en","type":"article","venue":"AIDS","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"DuPont","keywords":"Lamivudine; Indinavir; Efavirenz; Zidovudine; Reverse-transcriptase inhibitor; Tolerability; Regimen; Nelfinavir; Virology; Medicine; Pharmacology; Viral load; Gastroenterology; Internal medicine; Adverse effect; Human immunodeficiency virus (HIV); Virus; Viral disease; Antiretroviral therapy; Hepatitis B virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001494681,0.0002800774,0.0005621025,0.00009272834,0.0001567671,0.0003114019,0.0002491634,0.0004333305,0.001164373],"category_scores_gemma":[0.002201887,0.000120459,0.0004490174,0.0001275755,0.0002540323,0.0004209627,0.0001441621,0.0006910853,0.000138997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002265,"about_ca_system_score_gemma":0.0001741626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001994642,"about_ca_topic_score_gemma":0.0004059763,"domain_scores_codex":[0.9994117,0.0003110482,0.00005738979,0.00004452899,0.0001219588,0.00005326008],"domain_scores_gemma":[0.9990363,0.0003493559,0.0002975692,0.000048327,0.00006659478,0.0002018645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5353971,0.02041199,0.08914094,0.00145481,0.002472014,0.0004072249,0.0003246348,0.004380481,0.03855392,0.0001544962,0.000842074,0.3064604],"study_design_scores_gemma":[0.04497605,0.5715176,0.3659526,0.0002344324,0.001238066,0.001745256,0.0002023849,0.002531891,0.008359155,0.0002008931,0.002968156,0.00007345348],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955446,0.00379051,0.0001346707,0.00005787725,0.0000273216,0.00002613493,0.00006884343,0.000005874723,0.0003441853],"genre_scores_gemma":[0.9985373,0.0006787155,0.0001810593,0.00006060518,0.00007099025,0.00003322826,0.0001497317,0.000001575704,0.0002868447],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001494681,"threshold_uncertainty_score":0.007904708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02659385184629428,"score_gpt":0.2756971729500766,"score_spread":0.2491033211037823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}