{"id":"W2041480834","doi":"10.1371/journal.pgen.1002108","title":"Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT)","year":2011,"lang":"en","type":"review","venue":"PLoS Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Institute of Nursing Research; National Center on Minority Health and Health Disparities; National Human Genome Research Institute; National Institute on Aging; National Institute on Minority Health and Health Disparities; National Center for Research Resources; RIKEN; University of California, Irvine; Wake Forest University; Kaiser Foundation Research Institute; U.S. Public Health Service; Broad Institute; Jackson State University; Johns Hopkins University; National Heart, Lung, and Blood Institute; Northwestern University; University of Minnesota; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Biology; Genome-wide association study; Genetics; Genetic association; Locus (genetics); Linkage disequilibrium; Genotyping; SNP; Single-nucleotide polymorphism; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001263645,0.0006371799,0.002236314,0.0001298144,0.0001895596,0.00001238642,0.0006534001,0.0007346697,0.00002625382],"category_scores_gemma":[0.0008220958,0.0005079338,0.0003270551,0.0003903389,0.000182026,0.000002290673,0.0005600284,0.0004760875,0.000008603461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000205603,"about_ca_system_score_gemma":0.0002762352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001656886,"about_ca_topic_score_gemma":0.0009535818,"domain_scores_codex":[0.9939442,0.002181647,0.001848959,0.0009350282,0.0002009306,0.0008892429],"domain_scores_gemma":[0.9957666,0.0008523889,0.002157463,0.000886673,0.0001861365,0.0001507023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002154561,0.001101294,0.9877199,0.000745606,0.0014071,0.000005941404,0.0004973171,0.0003670656,0.00005074361,0.000005076862,0.0007277362,0.007350668],"study_design_scores_gemma":[0.0017806,0.002796645,0.1415156,0.0003819546,0.00520592,0.00002361271,0.000757079,0.00008575239,0.00002698897,0.0001652345,0.8459632,0.001297445],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2896944,0.7082448,0.00007845464,0.00003737184,0.0001681227,0.00145605,0.0000821931,0.00000832263,0.0002302804],"genre_scores_gemma":[0.1119618,0.8858094,0.0007728098,0.0001981892,0.0003997028,0.0003106829,0.0002267133,0.00008864655,0.0002320406],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8462043,"threshold_uncertainty_score":0.9997372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04449793617068237,"score_gpt":0.2877486655831037,"score_spread":0.2432507294124213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}