{"id":"W2041485880","doi":"10.1016/s0898-6568(02)00121-3","title":"The N-terminal non-RGS domain of human regulator of G-protein signalling 1 contributes to its ability to inhibit pheromone receptor signalling in yeast","year":2003,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Biology; GTPase-activating protein; RGS2; G protein; Cell biology; Mutant; Regulator of G protein signaling; Gene; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00268303,0.0004088228,0.0006321477,0.0001704014,0.0002649354,0.00006316912,0.0005607847,0.0003078659,0.00008906851],"category_scores_gemma":[0.0003045512,0.0003729018,0.0002725358,0.0005141608,0.0001092891,0.00001403244,0.0001535638,0.000266436,0.00001225249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007548752,"about_ca_system_score_gemma":0.0001527111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003727202,"about_ca_topic_score_gemma":0.00003847329,"domain_scores_codex":[0.99652,0.0003423316,0.00123093,0.0007719256,0.0004456713,0.000689121],"domain_scores_gemma":[0.998396,0.00008720006,0.0003874381,0.0004844001,0.0004024909,0.0002424761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002159429,0.0001289938,0.0001400741,0.0001123127,0.00006066916,0.000008189098,0.0003362473,0.004548676,0.9928499,0.001279909,0.00002327996,0.0002957907],"study_design_scores_gemma":[0.0007774301,0.0005705556,0.00001692563,0.0004681847,0.00002364145,0.000002068691,0.000516385,0.0002662747,0.9955407,0.000787184,0.0006366197,0.000393964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9297664,0.001537241,0.06726542,0.00005299779,0.0001402564,0.001076146,0.00002171522,0.00001514301,0.0001246804],"genre_scores_gemma":[0.993618,0.00002156259,0.005801183,0.00004887005,0.0001456366,0.0000936684,0.00003606261,0.00006949154,0.0001655311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06385159,"threshold_uncertainty_score":0.9998723,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0104016494852586,"score_gpt":0.2335402815608463,"score_spread":0.2231386320755877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}