{"id":"W2041524641","doi":"10.1128/jvi.01852-07","title":"Fusogenicity of Jaagsiekte Sheep Retrovirus Envelope Protein Is Dependent on Low pH and Is Enhanced by Cytoplasmic Tail Truncations","year":2007,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Infectious Diseases and Mycology","field":"Veterinary","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Syncytium; Biology; Cell fusion; Retrovirus; Ectodomain; Lipid bilayer fusion; Cytoplasm; Mutant; Fusion protein; Viral envelope; Amino acid; Molecular biology; Glycoprotein; Biochemistry; Virology; Cell; Virus; Receptor; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005012158,0.0001667123,0.0004118949,0.0002208976,0.00009593043,0.000009411617,0.0001651809,0.0002394275,0.0008771684],"category_scores_gemma":[0.000114992,0.0001491063,0.0001505198,0.0001072611,0.0001284139,0.00009233332,0.00005659007,0.0003718704,0.00003990597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001077238,"about_ca_system_score_gemma":0.0001076361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005829598,"about_ca_topic_score_gemma":0.0000347032,"domain_scores_codex":[0.9984796,0.0001306139,0.0006577868,0.00021006,0.0002019311,0.000320025],"domain_scores_gemma":[0.9987066,0.0001372682,0.0006403427,0.0001993855,0.000172265,0.0001441365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003568221,0.0005658413,0.002201744,0.00004118605,0.0002145687,0.0001247529,0.0005175606,0.00001037258,0.9856125,0.0001789632,0.002678277,0.004285998],"study_design_scores_gemma":[0.005493177,0.01992047,0.1026651,0.00007342038,0.0003076168,0.001627019,0.0002335975,0.00008023516,0.8595519,0.001761761,0.007819249,0.0004664153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960281,0.0003300525,0.001313954,0.0005082269,0.0002388487,0.0002259301,0.00005655155,0.000009731668,0.00128855],"genre_scores_gemma":[0.9975219,0.000193221,0.0002035294,0.001710619,0.0001276421,0.000007062903,0.000002567964,0.00001846911,0.0002149624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1260606,"threshold_uncertainty_score":0.960438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361659090774084,"score_gpt":0.2881424378706899,"score_spread":0.2745258469629491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}