{"id":"W2041524641","doi":"10.1128/jvi.01852-07","title":"Fusogenicity of Jaagsiekte Sheep Retrovirus Envelope Protein Is Dependent on Low pH and Is Enhanced by Cytoplasmic Tail Truncations","year":2007,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Infectious Diseases and Mycology","field":"Veterinary","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Syncytium; Biology; Cell fusion; Retrovirus; Ectodomain; Lipid bilayer fusion; Cytoplasm; Mutant; Fusion protein; Viral envelope; Amino acid; Molecular biology; Glycoprotein; Biochemistry; Virology; Cell; Virus; Receptor; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001413412,0.0002141398,0.0001988467,0.0001470577,0.00009609957,0.0002549461,0.0001038841,0.0002082563,0.0005056139],"category_scores_gemma":[0.0001966259,0.0001065088,0.000230428,0.00009790091,0.0001562254,0.0001736441,0.0002664715,0.0003508471,0.0001837362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001813219,"about_ca_system_score_gemma":0.00008831244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002970103,"about_ca_topic_score_gemma":0.0002690904,"domain_scores_codex":[0.9998487,0.00002855613,0.00001793724,0.00002139538,0.00004885752,0.00003460697],"domain_scores_gemma":[0.9998659,0.00004010273,0.00003754506,0.00001457286,0.0000167248,0.00002521745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003967146,0.000005372062,0.0001674219,0.00000614165,0.000001664213,0.0000280724,0.000005344973,0.00001718493,0.9995478,0.00001629658,0.000004783172,0.0001602573],"study_design_scores_gemma":[0.000005960409,0.0001636231,0.01041717,0.000003858188,0.000007850636,0.000333506,0.00002482185,0.0007095609,0.9877987,0.0000297092,0.0005005635,0.000004576992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998486,0.000369283,0.0006240572,0.00002383352,0.000004916552,0.000006646584,0.0001068052,0.00001376198,0.0003647853],"genre_scores_gemma":[0.9986873,0.0002266111,0.0003290967,0.00001888117,0.000002832798,0.000007644799,0.0002783406,0.00000864988,0.0004405679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005056139,"threshold_uncertainty_score":0.001691461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01361659090774084,"score_gpt":0.2881424378706899,"score_spread":0.2745258469629491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}