{"id":"W2041578893","doi":"10.1111/j.1755-148x.2009.00609.x","title":"Independent regulation of hair and skin color by two G protein‐coupled pathways","year":2009,"lang":"en","type":"article","venue":"Pigment Cell & Melanoma Research","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Melanocyte; Melanocortin 1 receptor; Epidermis (zoology); Cell biology; Melanin; Pigment; Mutant; Signal transduction; Hypopigmentation; Biology; Hedgehog signaling pathway; Pigmentation disorder; Hair follicle; Darkness; Chemistry; Genetics; Anatomy; Botany; Phenotype; Melanoma","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001902603,0.0004243641,0.0003522194,0.0003595645,0.0001397664,0.0005146205,0.0003290269,0.0004335912,0.0006445026],"category_scores_gemma":[0.0002497232,0.0002020568,0.0003570631,0.0001208203,0.0004738636,0.0003865505,0.0009289263,0.0005140204,0.000276513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003480797,"about_ca_system_score_gemma":0.0002151748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004710327,"about_ca_topic_score_gemma":0.0007978772,"domain_scores_codex":[0.9996196,0.00005197424,0.00001813455,0.000110998,0.0001055627,0.00009365415],"domain_scores_gemma":[0.9997306,0.00003802489,0.00006409359,0.00004144042,0.00003589137,0.00008982618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001015857,0.00001107528,0.0006238563,0.00001677938,0.000006849924,0.00005890332,0.0000129723,0.00004748083,0.9974214,0.000290253,0.00001801619,0.001390863],"study_design_scores_gemma":[0.0001697346,0.0007716264,0.1578131,0.00003065832,0.0001111898,0.001459738,0.000232574,0.003976131,0.8303334,0.001503498,0.00354694,0.00005140931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992322,0.001518875,0.003160624,0.0001133071,0.00003366916,0.00002461722,0.0001365772,0.00009431246,0.002596017],"genre_scores_gemma":[0.9954436,0.0005498742,0.001919445,0.000104581,0.00001042803,0.00002583783,0.000144659,0.00002671642,0.001774865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006445026,"threshold_uncertainty_score":0.002525508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02099467323800495,"score_gpt":0.3023659431151008,"score_spread":0.2813712698770959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}