{"id":"W2041578893","doi":"10.1111/j.1755-148x.2009.00609.x","title":"Independent regulation of hair and skin color by two G protein‐coupled pathways","year":2009,"lang":"en","type":"article","venue":"Pigment Cell & Melanoma Research","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Melanocyte; Melanocortin 1 receptor; Epidermis (zoology); Cell biology; Melanin; Pigment; Mutant; Signal transduction; Hypopigmentation; Biology; Hedgehog signaling pathway; Pigmentation disorder; Hair follicle; Darkness; Chemistry; Genetics; Anatomy; Botany; Phenotype; Melanoma","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008714828,0.0001324206,0.0001473735,0.00009223352,0.0001190294,0.00003739414,0.0001627019,0.0001253113,0.00005710842],"category_scores_gemma":[0.00003620001,0.0001246505,0.00004223763,0.0001219569,0.00008354434,0.000006361943,0.00009109319,0.0001330453,0.00001036384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003893294,"about_ca_system_score_gemma":0.00007011079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006142112,"about_ca_topic_score_gemma":0.00001655277,"domain_scores_codex":[0.9982657,0.0002103424,0.0002703017,0.0003867132,0.00054805,0.0003188529],"domain_scores_gemma":[0.9993197,0.00002210627,0.0000928611,0.0002964256,0.0001544173,0.0001144584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000217966,0.0002062377,0.000800016,0.00003408407,0.00001373811,0.000002412,0.0001244939,0.0000113423,0.9913028,0.0002855811,0.001480152,0.005521136],"study_design_scores_gemma":[0.001522255,0.001249726,0.009610123,0.00001831925,0.000006766187,0.000003426403,0.0001587111,0.000540508,0.9845651,0.0004438735,0.001748885,0.0001323552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945577,0.0007373082,0.0005289016,0.000160322,0.00004599781,0.0007843596,0.00001401943,0.000007718347,0.003163683],"genre_scores_gemma":[0.9969239,0.0001343215,0.0004281729,0.00003184915,0.0001162669,0.00006425769,0.0002364624,0.00001366399,0.002051151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008810107,"threshold_uncertainty_score":0.50831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02099467323800495,"score_gpt":0.3023659431151008,"score_spread":0.2813712698770959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}