{"id":"W2041602192","doi":"10.1023/b:trag.0000040036.11109.ee","title":"Production of Transgenic Tilapia with Brockmann Bodies Secreting [desThrB30] Human Insulin","year":2004,"lang":"en","type":"article","venue":"Transgenic Research","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Biology; Tilapia; Islet; Transgene; Xenotransplantation; Microinjection; Insulin; Beta cell; Transgenesis; Zebrafish; Molecular biology; Transplantation; Cell biology; Gene; Internal medicine; Cryopreservation; Endocrinology; Genetics; Embryo; Fish <Actinopterygii>; Fishery; Reproductive technology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001039615,0.0001853324,0.0004193297,0.0003804019,0.0002534846,0.00001886936,0.0001393382,0.0001188405,0.0003446174],"category_scores_gemma":[0.0001502932,0.0001438729,0.0001310551,0.0006395961,0.0004651026,0.0001225137,0.000011628,0.0005526119,0.00005654948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001132268,"about_ca_system_score_gemma":0.0003856779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002073059,"about_ca_topic_score_gemma":0.000102678,"domain_scores_codex":[0.9974822,0.0001312921,0.00040984,0.0004408602,0.0009915305,0.0005443078],"domain_scores_gemma":[0.9987344,0.00008650561,0.00005343807,0.0004618998,0.0004606048,0.0002031584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001947208,0.0007502496,0.01205371,0.001409909,0.0003518165,0.00001977105,0.005682353,0.0002493335,0.9733875,0.001113115,0.0004318816,0.00260311],"study_design_scores_gemma":[0.00899012,0.004227964,0.05578845,0.001167733,0.0002504908,0.00007010517,0.002018404,0.00001867745,0.9234375,0.001358162,0.002311376,0.0003609678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884095,0.0007958349,0.0002114805,0.001317298,0.00006655122,0.0007949672,0.000003643533,0.00009962802,0.008301106],"genre_scores_gemma":[0.9955165,0.0002435575,0.0007223479,0.00003559944,0.0001709956,0.00006962238,0.00002599812,0.00004126163,0.003174166],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04994999,"threshold_uncertainty_score":0.5866968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08787677022091968,"score_gpt":0.3701026192659299,"score_spread":0.2822258490450102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}