{"id":"W2041604111","doi":"10.1096/fj.07-8585com","title":"A structural basis for interferon‐α‐receptor interactions","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Extracellular; Biology; Docking (animal); Plasma protein binding; Protein structure; Chemistry; Biophysics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004513699,0.0001111036,0.0001531162,0.0001343245,0.0003917017,0.00006469972,0.0001116101,0.00003124876,0.002044579],"category_scores_gemma":[0.0001991705,0.00006633,0.0002597592,0.0001058767,0.00005020645,0.000126746,0.00002109923,0.0005066049,0.00005482858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001511392,"about_ca_system_score_gemma":0.00006906364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001909164,"about_ca_topic_score_gemma":0.00003689746,"domain_scores_codex":[0.9991553,0.0000221231,0.000318301,0.0001000689,0.0001485172,0.0002557303],"domain_scores_gemma":[0.9990578,0.0002915987,0.0001326959,0.0001563774,0.0002054801,0.0001560069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001117184,0.0000602392,0.00079802,0.00001140865,0.0001922632,0.00001194595,0.0009940608,0.00001764989,0.9643317,0.0003743329,0.01581995,0.01627117],"study_design_scores_gemma":[0.002231785,0.001464229,0.005777107,0.0003932742,0.000361174,0.007418886,0.004162146,0.001441273,0.8635311,0.0004438199,0.1125184,0.0002567605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722781,0.00007530492,0.01978125,0.003321485,0.001997238,0.0002227039,0.00002635936,0.0000351969,0.002262405],"genre_scores_gemma":[0.9939429,0.000008547585,0.001917958,0.0006667295,0.00179434,0.00000644825,0.00000875413,0.00001983136,0.001634512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1008006,"threshold_uncertainty_score":0.9988677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04194822265241367,"score_gpt":0.3251911814364558,"score_spread":0.2832429587840422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}