{"id":"W2041629314","doi":"10.1002/lt.21657","title":"Pharmacokinetics, efficacy, and safety of mycophenolate mofetil in combination with standard-dose or reduced-dose tacrolimus in liver transplant recipients","year":2009,"lang":"en","type":"article","venue":"Liver Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"F. Hoffmann-La Roche","keywords":"Tacrolimus; Pharmacokinetics; Medicine; Mycophenolate; Mycophenolic acid; Pharmacology; Liver transplantation; Urology; Trough level; Area under the curve; Gastroenterology; Transplantation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001971995,0.0002573078,0.0004426173,0.0003457497,0.00004379551,0.00001398692,0.00006422225,0.00009299981,0.00006124817],"category_scores_gemma":[0.00000502429,0.0001980924,0.00004618837,0.000386149,0.00005915705,0.0002207084,0.000002162973,0.0001984639,0.000003688943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001125631,"about_ca_system_score_gemma":0.00007331609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001765835,"about_ca_topic_score_gemma":0.0002046774,"domain_scores_codex":[0.9983252,0.0001084159,0.0005538673,0.0003575803,0.000387753,0.000267188],"domain_scores_gemma":[0.9994094,0.000141225,0.0001270724,0.0001332685,0.00007595118,0.0001130583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.4109022,0.006046582,0.3384993,0.004622838,0.0005676168,0.01633907,0.0569776,0.001999394,0.03450927,0.0008449791,0.00001025862,0.1286809],"study_design_scores_gemma":[0.04949036,0.002139752,0.9323058,0.002414798,0.0004292924,0.0004388776,0.00006656678,0.0009655008,0.01148306,0.00003381355,0.00001481743,0.0002173332],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969168,0.00027262,0.0008121822,0.0001573521,0.00006211191,0.001068685,0.0001976339,0.00003154272,0.0004810673],"genre_scores_gemma":[0.9835683,0.01437612,0.001399075,0.000105692,0.00001292178,0.00001463262,0.0004058809,0.00002073055,0.0000967282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5938065,"threshold_uncertainty_score":0.8077972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01738129961006038,"score_gpt":0.285379476643951,"score_spread":0.2679981770338906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}