{"id":"W2041629314","doi":"10.1002/lt.21657","title":"Pharmacokinetics, efficacy, and safety of mycophenolate mofetil in combination with standard-dose or reduced-dose tacrolimus in liver transplant recipients","year":2009,"lang":"en","type":"article","venue":"Liver Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"F. Hoffmann-La Roche","keywords":"Tacrolimus; Pharmacokinetics; Medicine; Mycophenolate; Mycophenolic acid; Pharmacology; Liver transplantation; Urology; Trough level; Area under the curve; Gastroenterology; Transplantation; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008685171,0.0003117307,0.0008365207,0.0001941558,0.0001503329,0.0004223358,0.0002807929,0.0003566392,0.0004745332],"category_scores_gemma":[0.002356141,0.0002439635,0.0004476423,0.0001688745,0.0005425373,0.0003516648,0.0001355044,0.0006143923,0.0001893821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005530337,"about_ca_system_score_gemma":0.0003142638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002899537,"about_ca_topic_score_gemma":0.0003623687,"domain_scores_codex":[0.9992968,0.0003605771,0.00005425894,0.00007307489,0.0001320443,0.00008339377],"domain_scores_gemma":[0.9991252,0.0003286638,0.0002626396,0.00007898243,0.00002794242,0.0001766194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3611157,0.01570335,0.1533089,0.0005306636,0.001446901,0.0007888111,0.000494366,0.007038162,0.212978,0.0002791056,0.0008594418,0.2454566],"study_design_scores_gemma":[0.02577052,0.6549513,0.2476965,0.00004921979,0.001309249,0.002309466,0.0001918729,0.01041413,0.05512159,0.0002522925,0.00186017,0.00007375256],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993425,0.000445553,0.00006980673,0.00001645083,0.000004777517,0.00001047262,0.000009861385,0.000005790088,0.00009466529],"genre_scores_gemma":[0.9994578,0.0001594204,0.0002106817,0.00003343689,0.00002471006,0.00001881238,0.0000375578,0.00000188645,0.0000557547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008685171,"threshold_uncertainty_score":0.004593194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01738129961006038,"score_gpt":0.285379476643951,"score_spread":0.2679981770338906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}