{"id":"W2041638315","doi":"10.1007/s00018-011-0660-3","title":"Alternative pathways for MHC class I presentation: a new function for autophagy","year":2011,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Antigen processing; MHC class I; Antigen presentation; Cross-presentation; Cell biology; Antigen; Biology; MHC restriction; Major histocompatibility complex; Autophagy; MHC class II; Transporter associated with antigen processing; Proteasome; Immune system; Immunology; T cell; Genetics; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003029599,0.0003202658,0.0008125502,0.0001792815,0.0002169628,0.00005243244,0.0002040112,0.0001929111,0.00005386067],"category_scores_gemma":[0.0001113863,0.0002383521,0.0005469117,0.0002166813,0.0002192544,0.00009630711,0.00003982191,0.0001082417,0.000009514747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002420629,"about_ca_system_score_gemma":0.00102718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000163941,"about_ca_topic_score_gemma":5.24217e-7,"domain_scores_codex":[0.998386,0.00006116356,0.000369696,0.0006328993,0.0002384392,0.0003118516],"domain_scores_gemma":[0.9989643,0.0001057965,0.0002577452,0.0002399524,0.00009266013,0.0003396152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000163856,0.0001563279,0.000001626835,0.008455135,0.0007724816,0.00003529998,0.0003009248,0.000002432603,0.0004618963,0.04428236,0.003010863,0.9423568],"study_design_scores_gemma":[0.001046699,0.0009720512,0.000001486277,0.001223743,0.001715777,0.00001501019,0.0000487677,0.0002704807,0.001960038,0.01018858,0.9822689,0.0002885067],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009364958,0.923516,0.07249398,0.00004225348,0.0005536183,0.002299992,0.00004645265,0.00004143545,0.0009126057],"genre_scores_gemma":[0.0003708942,0.9948522,0.001658719,0.0006034671,0.0006890199,0.0004830603,0.000235439,0.00004715579,0.001060064],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.979258,"threshold_uncertainty_score":0.9719716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1012425796117993,"score_gpt":0.3544273640283211,"score_spread":0.2531847844165218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}