{"id":"W2041667477","doi":"10.1152/ajpheart.00199.2003","title":"Progressive apoptotic cell death triggered by transient oxidative insult in H9c2 rat ventricular cells: a novel pattern of apoptosis and the mechanisms","year":2004,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Programmed cell death; Apoptosis; Oxidative stress; Dichlorofluorescein; Cell biology; Reactive oxygen species; Intracellular; Cytochrome c; Mitochondrion; Oxidative phosphorylation; Chemistry; Fragmentation (computing); Biology; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001306711,0.0005106464,0.0004020818,0.000343274,0.0001504981,0.0002214557,0.00027397,0.0004175165,0.0005717141],"category_scores_gemma":[0.0001041434,0.0001090337,0.0002816633,0.0002481558,0.0002758624,0.0002645093,0.0001991074,0.0005527797,0.0002291979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002289944,"about_ca_system_score_gemma":0.0001265579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004175064,"about_ca_topic_score_gemma":0.0006070649,"domain_scores_codex":[0.9998643,0.000014925,0.00001347508,0.00003795353,0.00003937903,0.00002990409],"domain_scores_gemma":[0.9998664,0.00001289062,0.00004831704,0.00001940993,0.0000281505,0.00002492897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002051193,0.00002695925,0.0003864835,0.00007190191,0.000009184153,0.0003871385,0.00003068066,0.00003989517,0.9969958,0.00007328096,0.00002943613,0.001744039],"study_design_scores_gemma":[0.00004830123,0.001201257,0.03064944,0.00001803699,0.00004796837,0.002559715,0.00007840997,0.000853203,0.9625701,0.0002165122,0.001742909,0.00001417802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749391,0.007717818,0.01406659,0.0001062828,0.00008167078,0.0001136104,0.0007280629,0.000236158,0.002010606],"genre_scores_gemma":[0.9892975,0.002651253,0.005544023,0.00008748871,0.00004416536,0.0001199892,0.0005509318,0.00002189862,0.001682755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005717141,"threshold_uncertainty_score":0.001912594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00528315487246092,"score_gpt":0.2084316751333566,"score_spread":0.2031485202608957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}