{"id":"W2041681732","doi":"10.1155/2010/696034","title":"Phenotypic Transition of the Collecting Duct Epithelium in Congenital Urinary Tract Obstruction","year":2009,"lang":"en","type":"article","venue":"Journal of Biomedicine and Biotechnology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; Child and Family Research Institute; University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; American Society of Nephrology","keywords":"Epithelial–mesenchymal transition; Epithelium; Cholangiocyte; Extracellular matrix; Pathology; Basement membrane; Duct (anatomy); Fibrosis; Mesenchymal stem cell; Urinary system; Kidney development; Biology; Urinary tract obstruction; Phenotype; Mesenchyme; Kidney; Medicine; Anatomy; Cell biology; Endocrinology; Downregulation and upregulation; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001386433,0.00006743646,0.0001500996,0.0001558534,0.00003064258,0.000001855456,0.00008464992,0.0002444912,0.000002157514],"category_scores_gemma":[0.00002888022,0.00003977684,0.00005669306,0.0002557364,0.000174865,0.000004099378,0.0000103451,0.000207761,7.608372e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001347832,"about_ca_system_score_gemma":0.00004436018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000862875,"about_ca_topic_score_gemma":0.000002480425,"domain_scores_codex":[0.9994483,0.00002615203,0.0002770858,0.00008306542,0.00007236384,0.00009301001],"domain_scores_gemma":[0.9996607,0.000005490712,0.0001971764,0.00007242699,0.00004285632,0.00002129982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001802854,0.00008467823,0.0003268051,0.00001037798,0.0000317141,0.00001642243,0.0000728836,0.00001133061,0.9775746,0.00001949752,0.00005981082,0.02161157],"study_design_scores_gemma":[0.002371677,0.0059085,0.03037838,0.0001566186,0.00008207847,0.004865882,0.0008657767,0.00004204877,0.9522154,0.000996443,0.001999345,0.0001178424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905757,0.002795774,0.0001392946,0.006157232,0.0002104023,0.00005677546,0.000001801001,0.000002136129,0.00006091345],"genre_scores_gemma":[0.9980225,0.001601209,0.00008830494,0.0001280273,0.0001322994,2.646512e-7,0.000001435943,0.000002867315,0.00002310842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03005158,"threshold_uncertainty_score":0.188574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005070015902876196,"score_gpt":0.222693398034372,"score_spread":0.2176233821314958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}