{"id":"W2041681732","doi":"10.1155/2010/696034","title":"Phenotypic Transition of the Collecting Duct Epithelium in Congenital Urinary Tract Obstruction","year":2009,"lang":"en","type":"article","venue":"Journal of Biomedicine and Biotechnology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; Child and Family Research Institute; University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; American Society of Nephrology","keywords":"Epithelial–mesenchymal transition; Epithelium; Cholangiocyte; Extracellular matrix; Pathology; Basement membrane; Duct (anatomy); Fibrosis; Mesenchymal stem cell; Urinary system; Kidney development; Biology; Urinary tract obstruction; Phenotype; Mesenchyme; Kidney; Medicine; Anatomy; Cell biology; Endocrinology; Downregulation and upregulation; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001891456,0.00009022824,0.0001659782,0.0004572098,0.0001764856,0.0002169942,0.00009620923,0.0001763269,0.0006086845],"category_scores_gemma":[0.0004474453,0.0001108729,0.0001023006,0.0001792097,0.0002782362,0.0001412582,0.0002331954,0.0002519526,0.0001031344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001701921,"about_ca_system_score_gemma":0.0002160594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005390206,"about_ca_topic_score_gemma":0.0005392678,"domain_scores_codex":[0.9998698,0.00003285123,0.00001070102,0.00002002113,0.00004648322,0.00002007811],"domain_scores_gemma":[0.9997934,0.00003724265,0.0000622175,0.00002389178,0.00002308227,0.00006017774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003618418,0.00003633462,0.02259558,0.00009135585,0.00001583631,0.004137959,0.0002461396,0.0003240598,0.9623702,0.0006893268,0.0001115739,0.009019866],"study_design_scores_gemma":[0.00002449997,0.0005839606,0.5678256,0.00002297664,0.00005403878,0.04385631,0.0004624143,0.001846868,0.3786232,0.0007118817,0.005962406,0.00002580979],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996224,0.001207009,0.001423694,0.00004626478,0.000008018426,0.00000975599,0.00006952641,0.00003069357,0.0009808379],"genre_scores_gemma":[0.9989073,0.0003509006,0.0004406107,0.00001127822,0.000002521235,0.000004062709,0.00004853941,0.000003974225,0.0002308117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006086845,"threshold_uncertainty_score":0.002036273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005070015902876196,"score_gpt":0.222693398034372,"score_spread":0.2176233821314958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}