{"id":"W2041711732","doi":"10.1371/journal.pcbi.1000910","title":"Gene Expression Variability within and between Human Populations and Implications toward Disease Susceptibility","year":2010,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Genetics; Gene expression; Gene; Population; Gene expression profiling; International HapMap Project; Phenotype; Regulation of gene expression; Human genome; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001310433,0.0001484374,0.0004751549,0.0005749226,0.0002559196,0.0005969307,0.0002515386,0.0003702083,0.0006251295],"category_scores_gemma":[0.004183278,0.000208858,0.0003070664,0.0007939609,0.0007949671,0.0002746921,0.0004138129,0.000405095,0.00007116814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001932281,"about_ca_system_score_gemma":0.0001280097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001118109,"about_ca_topic_score_gemma":0.0009369302,"domain_scores_codex":[0.9990966,0.0003297492,0.000039155,0.0004057092,0.00006944048,0.00005934621],"domain_scores_gemma":[0.9984451,0.001030493,0.0001945093,0.0002264755,0.00005458071,0.00004889225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007956339,0.00007205018,0.8682877,0.0001272474,0.0008333267,0.0004932501,0.0009150291,0.01089434,0.08106045,0.002762157,0.0003952622,0.03336356],"study_design_scores_gemma":[0.00002084202,0.0001071265,0.9735878,0.00001233275,0.0001539356,0.0005418509,0.0002872842,0.01325953,0.003299145,0.007961953,0.0007409335,0.00002724918],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935936,0.0004193746,0.005126164,0.0001214906,0.000006198055,0.000005176575,0.0003016416,0.00002370494,0.0004027459],"genre_scores_gemma":[0.9986848,0.000118239,0.0008366351,0.00004529419,0.000007524708,0.000007936064,0.0002196477,0.000007848305,0.00007219329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001310433,"threshold_uncertainty_score":0.006930351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05378459939670064,"score_gpt":0.3307944958117779,"score_spread":0.2770098964150773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}