{"id":"W2041801904","doi":"10.1038/sj.gt.3302074","title":"Illegitimate DNA integration in mammalian cells","year":2003,"lang":"en","type":"review","venue":"Gene Therapy","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; McGill University; Université de Montréal","funders":"","keywords":"Biology; Genome; Genetics; DNA; Computational biology; Locus (genetics); Gene; Genome instability; DNA damage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001497215,0.0003174307,0.0004857077,0.00009325184,0.00002161212,0.00002205312,0.00018691,0.0003065893,0.00004846328],"category_scores_gemma":[0.000004197032,0.0002741404,0.0002249759,0.0001265734,0.00001854716,0.000001171394,0.00002445697,0.0001321729,0.00003243088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002274475,"about_ca_system_score_gemma":0.00007011928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005571451,"about_ca_topic_score_gemma":0.00001152866,"domain_scores_codex":[0.9989148,0.00007921781,0.0003168312,0.0003622421,0.00007570269,0.0002512004],"domain_scores_gemma":[0.9994475,0.00000529709,0.00007873959,0.0003977036,0.00002030719,0.00005044368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006254201,0.0000251631,4.126027e-7,0.000305998,0.0000361304,0.000004749027,0.00001958847,0.00003059824,0.02782169,0.000007513058,0.0006868317,0.9710551],"study_design_scores_gemma":[0.0002052502,0.00007863779,0.000001340609,0.00029085,0.00001862926,0.00001764313,0.000005549662,0.000002712176,0.05449218,0.000007603841,0.9445889,0.0002907187],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004249283,0.9967963,0.001439032,0.000004175718,0.0003583383,0.0004354056,0.00002560704,0.00001010319,0.000506182],"genre_scores_gemma":[0.00008751891,0.9976762,0.0007394886,0.00006169924,0.0002092131,0.00009253104,0.0003286555,0.00006527208,0.000739441],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9707643,"threshold_uncertainty_score":0.9999711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02180882947428856,"score_gpt":0.3355680229535563,"score_spread":0.3137591934792677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}