{"id":"W2041956415","doi":"10.1016/j.tips.2005.04.003","title":"Nitrosative stress and pharmacological modulation of heart failure","year":2005,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":236,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institutes of Health","keywords":"Peroxynitrite; Nitric oxide; Matrix metalloproteinase; Poly ADP ribose polymerase; Peroxynitrous acid; Oxidative stress; Superoxide; Heart failure; Chemistry; Pharmacology; Reactive nitrogen species; Medicine; Enzyme; Biochemistry; Cell biology; Polymerase; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006060131,0.001207501,0.002433993,0.001910569,0.0002687036,0.0008781612,0.001084051,0.001046569,0.003501987],"category_scores_gemma":[0.0007336047,0.0002876927,0.0005470841,0.001691999,0.0005809363,0.001216103,0.0005397963,0.002046628,0.00229891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003669025,"about_ca_system_score_gemma":0.000773863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008214595,"about_ca_topic_score_gemma":0.001895245,"domain_scores_codex":[0.9998472,0.00002132129,0.00003222125,0.00003140864,0.00005299109,0.00001488053],"domain_scores_gemma":[0.9996172,0.0001804339,0.00006869801,0.00001252784,0.00008331604,0.00003774882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002609973,0.0002178266,0.0002185528,0.01738959,0.0001786224,0.0003335276,0.00004385314,0.0002793086,0.002346275,0.00154542,0.02261698,0.954569],"study_design_scores_gemma":[0.0001713107,0.0004315224,0.002579861,0.00446113,0.0005559235,0.002332888,0.00007914587,0.0001938757,0.0008478365,0.002021995,0.9862866,0.00003802973],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000134058,0.9984964,0.0001557237,0.0001821907,0.0002804344,0.000006978345,0.00001493717,0.000007267662,0.0007219289],"genre_scores_gemma":[0.0006204919,0.9981495,0.0002216982,0.0001729168,0.0003976134,0.000008708117,0.00002642901,0.000001079205,0.0004016368],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003501987,"threshold_uncertainty_score":0.01171529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09225302523614785,"score_gpt":0.4450258859404792,"score_spread":0.3527728607043313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}