{"id":"W2041973311","doi":"10.3390/ijerph8010117","title":"Constitutive, but Not Challenge-Induced, Interleukin-10 Production Is Robust in Acute Pre-Pubescent Protein and Energy Deficits: New Support for the Tolerance Hypothesis of Malnutrition-Associated Immune Depression Based on Cytokine Production in vivo","year":2011,"lang":"en","type":"article","venue":"International Journal of Environmental Research and Public Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Immune system; Cytokine; Immunology; Malnutrition; Depression (economics); Medicine; Interleukin 10; Intensive care medicine; Internal medicine; Economics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003619917,0.0004103019,0.0002631881,0.0003182968,0.00008132809,0.0003914948,0.0001841152,0.0002899736,0.0008966736],"category_scores_gemma":[0.0002349787,0.000136428,0.0002144982,0.0001779305,0.0004551449,0.0002685632,0.0002286494,0.001405364,0.0003057941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001347307,"about_ca_system_score_gemma":0.0001655786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001206011,"about_ca_topic_score_gemma":0.0002348638,"domain_scores_codex":[0.999833,0.00002482172,0.00003093707,0.00003636548,0.00003772587,0.00003697353],"domain_scores_gemma":[0.999474,0.000110633,0.0001339623,0.0001009499,0.00006012083,0.0001203647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000199099,0.00004605357,0.0008741808,0.00005963948,0.000003029748,0.00005467923,0.0000272538,0.00001811339,0.9977112,0.0000329988,0.00000969304,0.0009640396],"study_design_scores_gemma":[0.00004584731,0.001831322,0.04287823,0.00002761812,0.00002943249,0.0007535788,0.0001327012,0.0004817684,0.9523497,0.0001726602,0.001286772,0.00001044451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931206,0.001568126,0.003893105,0.0001200487,0.00003907306,0.00003687563,0.0003622029,0.00005070331,0.000809332],"genre_scores_gemma":[0.994004,0.001225295,0.003024621,0.00009673592,0.00004060946,0.00007281503,0.0005206782,0.00001400631,0.001001156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008966736,"threshold_uncertainty_score":0.002999663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1029221507248485,"score_gpt":0.3158875694236828,"score_spread":0.2129654186988343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}