{"id":"W2041973311","doi":"10.3390/ijerph8010117","title":"Constitutive, but Not Challenge-Induced, Interleukin-10 Production Is Robust in Acute Pre-Pubescent Protein and Energy Deficits: New Support for the Tolerance Hypothesis of Malnutrition-Associated Immune Depression Based on Cytokine Production in vivo","year":2011,"lang":"en","type":"article","venue":"International Journal of Environmental Research and Public Health","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Immune system; Cytokine; Immunology; Malnutrition; Depression (economics); Medicine; Interleukin 10; Intensive care medicine; Internal medicine; Economics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001130274,0.000109869,0.0001808846,0.0004410769,0.00009991606,0.00003567645,0.000250185,0.00005648567,0.00009077173],"category_scores_gemma":[0.000896487,0.00008461683,0.00004109046,0.0001583801,0.0002287369,0.0003365168,0.00005118435,0.0002824323,4.534862e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000321176,"about_ca_system_score_gemma":0.0002848471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002127285,"about_ca_topic_score_gemma":0.0001074105,"domain_scores_codex":[0.9979997,0.0002487286,0.0004865457,0.0002921371,0.0006876834,0.0002852442],"domain_scores_gemma":[0.9991624,0.0002283066,0.0002960933,0.0001122244,0.00007410203,0.0001268104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01227528,0.009511701,0.00692139,0.0001400162,0.0001018454,0.00005286909,0.002909776,0.0001936166,0.6831033,0.0008455233,0.0008335321,0.2831112],"study_design_scores_gemma":[0.00495032,0.003369096,0.1057114,0.0007592633,0.000004451345,0.00008749415,0.001070472,0.001000476,0.8797913,0.0006934151,0.002363915,0.0001983444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876574,0.0001913003,0.0001515602,0.01111208,0.000150112,0.000537366,0.00008290424,0.00000348119,0.0001137854],"genre_scores_gemma":[0.9974685,0.001750941,0.000194039,0.0002401945,0.00006121863,0.00003432711,0.000003337494,0.00001008427,0.0002374002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2829128,"threshold_uncertainty_score":0.3450574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1029221507248485,"score_gpt":0.3158875694236828,"score_spread":0.2129654186988343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}