{"id":"W2041999478","doi":"10.1016/j.peptides.2014.07.029","title":"Peptides derived from central turn motifs within integrin αIIb and αV cytoplasmic tails inhibit integrin activation","year":2014,"lang":"en","type":"article","venue":"Peptides","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Integrin; Vitronectin; Peptide; RGD motif; Chinese hamster ovary cell; Collagen receptor; Platelet Glycoprotein GPIIb-IIIa Complex; CD49c; Integrin, beta 6; Integrin alpha M; Cytoplasm; Cell adhesion; Chemistry; Molecular biology; Cell biology; Biology; Biochemistry; Receptor; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003842303,0.0003320102,0.0004742821,0.0002481371,0.0001241612,0.0001205004,0.0001809648,0.0001998869,0.0003437945],"category_scores_gemma":[0.001514688,0.0002732967,0.0001139388,0.0002375027,0.0002539578,0.0002254861,0.0002044585,0.0007775562,0.0001877246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002097447,"about_ca_system_score_gemma":0.0001260642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001287403,"about_ca_topic_score_gemma":0.0004969227,"domain_scores_codex":[0.9976448,0.0001485411,0.0004691178,0.0006155014,0.00056407,0.0005579559],"domain_scores_gemma":[0.9983448,0.0004498239,0.0001541564,0.0004567041,0.0001833399,0.0004111759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004068909,0.0001305731,0.0488358,0.0001040488,0.00006259731,0.0000258705,0.002071981,0.00004456727,0.9302368,0.000198157,0.000947633,0.01693511],"study_design_scores_gemma":[0.002012423,0.0003956294,0.1809303,0.0006041771,0.00005907131,0.00003570782,0.00156086,0.006894208,0.8037725,0.001416059,0.001967866,0.0003511561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943157,0.0000866746,0.002087633,0.0009546339,0.0001196796,0.0004888935,0.00001320532,0.0001384889,0.001795021],"genre_scores_gemma":[0.9931939,0.00007444905,0.004231678,0.0004275431,0.0003157147,0.0000330288,0.0001134962,0.00006159493,0.001548554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1320945,"threshold_uncertainty_score":0.9999719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01636001881199746,"score_gpt":0.2599317793871345,"score_spread":0.243571760575137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}