{"id":"W2041999478","doi":"10.1016/j.peptides.2014.07.029","title":"Peptides derived from central turn motifs within integrin αIIb and αV cytoplasmic tails inhibit integrin activation","year":2014,"lang":"en","type":"article","venue":"Peptides","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Integrin; Vitronectin; Peptide; RGD motif; Chinese hamster ovary cell; Collagen receptor; Platelet Glycoprotein GPIIb-IIIa Complex; CD49c; Integrin, beta 6; Integrin alpha M; Cytoplasm; Cell adhesion; Chemistry; Molecular biology; Cell biology; Biology; Biochemistry; Receptor; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001459808,0.0003948094,0.0002401675,0.0001651486,0.0001729842,0.0003461871,0.0002165422,0.0003061181,0.002099185],"category_scores_gemma":[0.000203465,0.0001610625,0.0002003832,0.0001314708,0.0001778908,0.0001888552,0.0001842838,0.0006665419,0.0004275179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001848834,"about_ca_system_score_gemma":0.0001590232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002858208,"about_ca_topic_score_gemma":0.000563432,"domain_scores_codex":[0.9998205,0.00003707816,0.000007995804,0.00001523664,0.00002730512,0.00009185741],"domain_scores_gemma":[0.9998699,0.00005126177,0.00001933285,0.0000100699,0.00001250536,0.00003690462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004968813,0.0000787876,0.0001018232,0.00003583412,0.000009529823,0.00006460799,0.0000144001,0.000140766,0.9970636,0.0001328026,0.00007652584,0.001784509],"study_design_scores_gemma":[0.0001565561,0.001367439,0.002495515,0.00001138696,0.00002760943,0.0003929577,0.00003716481,0.0007103568,0.992808,0.00009222393,0.001895093,0.000005672664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994664,0.001765037,0.0008411253,0.00004837435,0.00004914222,0.00003063737,0.00007360038,0.00001582059,0.002512398],"genre_scores_gemma":[0.9966477,0.0007570111,0.0006786994,0.00007947709,0.00002705594,0.0000199577,0.000240603,0.000009849896,0.001539634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002099185,"threshold_uncertainty_score":0.0070225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01636001881199746,"score_gpt":0.2599317793871345,"score_spread":0.243571760575137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}