{"id":"W2042015957","doi":"10.1021/ac026258k","title":"Ion Sensing and Inhibition Studies Using the Transmembrane Ion Channel Peptide Gramicidin A Entrapped in Sol−Gel-Derived Silica","year":2003,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Ontario Innovation Trust","keywords":"Chemistry; Gramicidin; Membrane; Ion channel; Melittin; Biophysics; Chromatography; Peptide; Vesicle; Ionophore; Ion; Liposome; Biochemistry; Receptor; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001848094,0.0004445949,0.0002872572,0.0001126611,0.0001103469,0.0002132461,0.0002182912,0.0003173342,0.0003233058],"category_scores_gemma":[0.0001894119,0.0001569584,0.0002948882,0.0001193639,0.0002071878,0.0002136034,0.0001637129,0.0002696411,0.0001699855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002844566,"about_ca_system_score_gemma":0.0001225354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001035381,"about_ca_topic_score_gemma":0.0006997602,"domain_scores_codex":[0.9998585,0.00002410973,0.00001293711,0.00003237581,0.00004428576,0.00002764912],"domain_scores_gemma":[0.9998807,0.00004818571,0.00002840047,0.000008383905,0.00002030823,0.00001413475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001797453,0.000005367808,0.00002163311,0.00001082708,0.000001656875,0.000006472899,0.000006485999,0.0000473021,0.999734,0.000007343672,0.000002378291,0.000138538],"study_design_scores_gemma":[0.000002864633,0.00007669639,0.0003372124,0.000001076381,0.000003274816,0.00001214386,0.000003864001,0.000653444,0.9988017,0.000003556579,0.0001022076,0.000001837776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969822,0.0004331328,0.00196513,0.00002483806,0.000009411617,0.00001903616,0.00005823625,0.00004195144,0.0004659506],"genre_scores_gemma":[0.9942385,0.0007121552,0.003845943,0.00003080714,0.000007940177,0.00002783966,0.00017063,0.00001984347,0.0009462498],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001035381,"threshold_uncertainty_score":0.00206393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02365723189216368,"score_gpt":0.2797907639198942,"score_spread":0.2561335320277305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}