{"id":"W2042015957","doi":"10.1021/ac026258k","title":"Ion Sensing and Inhibition Studies Using the Transmembrane Ion Channel Peptide Gramicidin A Entrapped in Sol−Gel-Derived Silica","year":2003,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Ontario Innovation Trust","keywords":"Chemistry; Gramicidin; Membrane; Ion channel; Melittin; Biophysics; Chromatography; Peptide; Vesicle; Ionophore; Ion; Liposome; Biochemistry; Receptor; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001842582,0.0002093626,0.0002290205,0.00002147543,0.0001102156,0.00002622785,0.00005557106,0.0001914363,0.000009263718],"category_scores_gemma":[0.0001240144,0.0001599364,0.00009398853,0.0001116653,0.0002088106,0.0000063698,0.0000333291,0.000190784,5.410915e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002668994,"about_ca_system_score_gemma":0.00004431234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002063098,"about_ca_topic_score_gemma":0.00002718485,"domain_scores_codex":[0.9988592,0.00005877508,0.0002589684,0.0003888541,0.0001304294,0.0003038174],"domain_scores_gemma":[0.9995636,0.00002616172,0.00005627657,0.0002132061,0.00006167336,0.00007908231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004469203,0.0000313077,0.0001557947,0.00007593024,0.00003858382,0.0000125823,0.0001330657,0.00005116187,0.9992796,0.000008840449,0.00002476682,0.0001436664],"study_design_scores_gemma":[0.0006559854,0.00003051336,0.0001609777,0.00005396513,0.00009704583,0.00009441733,0.0007233021,0.0005393189,0.9971331,0.000103151,0.0002051629,0.0002031005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987006,0.0003231595,0.0002558069,0.0002550443,0.00005098741,0.0001342904,0.000005110602,0.00001063294,0.0002644341],"genre_scores_gemma":[0.999203,0.0001681191,0.0000847327,0.000176135,0.0001876193,0.000003352291,0.00003923226,0.00001745875,0.0001203932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002146548,"threshold_uncertainty_score":0.6522019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02365723189216368,"score_gpt":0.2797907639198942,"score_spread":0.2561335320277305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}