{"id":"W2042023245","doi":"10.1016/j.ymgme.2009.12.005","title":"A Pex7 hypomorphic mouse model for plasmalogen deficiency affecting the lens and skeleton","year":2009,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital; McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health; Johns Hopkins University; Duke Endowment","keywords":"Plasmalogen; Phytanic acid; Endocrinology; Internal medicine; Endochondral ossification; Biology; Cataracts; Zellweger syndrome; Peroxisome; Phenotype; Biochemistry; Medicine; Genetics; Cartilage; Receptor; Anatomy; Gene; Phospholipid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002412934,0.0002590746,0.0002123102,0.00005270574,0.0002400265,0.00007172976,0.0001742573,0.000190084,9.179421e-7],"category_scores_gemma":[0.00009143401,0.0002040694,0.00009375447,0.00008063331,0.0001057081,0.000005235429,0.0001018106,0.0001266063,6.327311e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005846749,"about_ca_system_score_gemma":0.00005879357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000365649,"about_ca_topic_score_gemma":0.000004375185,"domain_scores_codex":[0.9987291,0.00006298277,0.0001975659,0.0004777302,0.0001394063,0.0003932236],"domain_scores_gemma":[0.9993659,0.00001451655,0.0000825232,0.0003329371,0.00008833186,0.0001157687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003332542,0.00003650615,0.00006994533,0.00001027381,0.00003344845,6.389513e-7,0.0001294948,0.0009483841,0.9921962,0.0005744402,0.00004724281,0.005920109],"study_design_scores_gemma":[0.0008815836,0.0002126096,0.0005256485,0.000005107928,0.0001000585,0.00002496471,0.00004704151,0.01041511,0.9811341,0.0006807073,0.005633901,0.0003392039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659072,0.01362183,0.0194102,0.0003441019,0.00007251668,0.0004890974,0.00003706855,0.00001642826,0.0001016179],"genre_scores_gemma":[0.9925144,0.002249334,0.003942961,0.0009607342,0.0001115979,0.00003841942,0.00003084652,0.00003762845,0.0001141169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02660722,"threshold_uncertainty_score":0.832171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01205149298719891,"score_gpt":0.2338358156127231,"score_spread":0.2217843226255242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}