{"id":"W2042036664","doi":"10.4161/cc.22935","title":"Micromanaging a large tumor suppressor","year":2012,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"","keywords":"Biology; microRNA; Gene silencing; Oncogene; Untranslated region; Gene; Drosha; Genetics; RNA; Cancer research; Cell cycle; RNA interference","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000858264,0.0002512913,0.0001719969,0.00005009078,0.00006853166,0.00003442648,0.0002794608,0.0004234269,0.0002693816],"category_scores_gemma":[0.00001119545,0.0002689169,0.0001674919,0.00003925763,0.0000362547,0.000003068736,0.00019973,0.0003220881,0.0002566447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002434036,"about_ca_system_score_gemma":0.00004336729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007062245,"about_ca_topic_score_gemma":0.000001641759,"domain_scores_codex":[0.9987099,0.00006506041,0.0001771219,0.0004120925,0.0001298554,0.0005060261],"domain_scores_gemma":[0.9991248,0.00000704752,0.0001360134,0.0006250058,0.00003885297,0.00006824644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000449308,0.00002457148,0.0000563647,0.0001263839,0.00002171192,0.00002232714,0.000009290738,0.000001581265,0.3705515,6.466698e-7,0.6291621,0.00001899807],"study_design_scores_gemma":[0.0002259699,0.00001093163,0.0002063862,0.00001612149,0.0000517922,0.00001161021,0.000003631222,0.00001096269,0.2288404,0.00001454096,0.7703495,0.0002580911],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8333492,0.02967591,0.001469475,0.09517895,0.003037324,0.001887501,0.001318689,0.0002169801,0.03386595],"genre_scores_gemma":[0.533581,0.00005316666,0.0008401372,0.4254131,0.0147301,0.0001011356,0.009528306,0.0003242588,0.01542889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3302341,"threshold_uncertainty_score":0.9999763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005785761528996537,"score_gpt":0.2147188522966953,"score_spread":0.2089330907676988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}