{"id":"W2042036664","doi":"10.4161/cc.22935","title":"Micromanaging a large tumor suppressor","year":2012,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sunnybrook Hospital; Sunnybrook Health Science Centre","funders":"","keywords":"Biology; microRNA; Gene silencing; Oncogene; Untranslated region; Gene; Drosha; Genetics; RNA; Cancer research; Cell cycle; RNA interference","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002807225,0.0002841837,0.0002383373,0.000333206,0.0004471479,0.0006336035,0.0004231468,0.000350965,0.006631556],"category_scores_gemma":[0.0003765078,0.0001545118,0.0001939003,0.0001872869,0.0005041915,0.0004742868,0.0006588808,0.0006277654,0.001997206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004620298,"about_ca_system_score_gemma":0.0004160382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004139709,"about_ca_topic_score_gemma":0.0005312379,"domain_scores_codex":[0.9998288,0.0000157235,0.000005690528,0.00006364935,0.00006785073,0.00001821535],"domain_scores_gemma":[0.999879,0.00002345113,0.00002775959,0.00001942458,0.00001857892,0.00003171376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001365965,0.00006383914,0.0007163432,0.0001160309,0.00001427837,0.0002108009,0.00009003999,0.0005789009,0.934507,0.01658431,0.002472428,0.04450947],"study_design_scores_gemma":[0.00007422478,0.0006637407,0.001341485,0.00001628118,0.00003210537,0.001092011,0.00007987205,0.004463932,0.8127686,0.004698675,0.1747485,0.0000206553],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.7000299,0.03998047,0.1632295,0.004152217,0.002532254,0.0004526088,0.0008467133,0.005055337,0.08372101],"genre_scores_gemma":[0.9311298,0.004194858,0.02191373,0.0006736717,0.0002077355,0.0002003682,0.0004289142,0.0002056447,0.04104519],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.006631556,"threshold_uncertainty_score":0.02218473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005785761528996537,"score_gpt":0.2147188522966953,"score_spread":0.2089330907676988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}