{"id":"W2042068855","doi":"10.1021/la8026489","title":"Optimization of Immobilized Bacterial Disaccharides for Surface Plasmon Resonance Imaging Measurements of Antibody Binding","year":2008,"lang":"en","type":"article","venue":"Langmuir","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Disaccharide; Surface plasmon resonance; Chemistry; Monolayer; Linker; Epitope; Molecule; Biophysics; Stereochemistry; Combinatorial chemistry; Organic chemistry; Biochemistry; Nanotechnology; Antibody; Nanoparticle; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000822861,0.001007102,0.0004795612,0.0003287149,0.0002463911,0.0005666753,0.0006279381,0.0003526191,0.0005752092],"category_scores_gemma":[0.0006532376,0.0004261705,0.000232399,0.0004606085,0.0002539415,0.0002713959,0.0003002801,0.0006468108,0.000318911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000616996,"about_ca_system_score_gemma":0.0003380004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001494318,"about_ca_topic_score_gemma":0.004013347,"domain_scores_codex":[0.999313,0.0001960897,0.00006702661,0.0001047132,0.000227499,0.00009163364],"domain_scores_gemma":[0.9997022,0.0001127393,0.00005501196,0.00002646967,0.00007361414,0.00002988756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002458717,0.00001668704,0.00005468127,0.00001857852,0.000002401714,0.000005366986,0.000007308317,0.0001347659,0.9991587,0.00002280013,0.000007212413,0.000546952],"study_design_scores_gemma":[0.000004975332,0.00005995101,0.000411896,0.000002227441,0.000004545406,0.00001028993,0.000008991824,0.001071072,0.9981375,0.00001255938,0.0002719768,0.000004006803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636856,0.001255509,0.03335816,0.0001265436,0.00003076765,0.0002396378,0.0002544213,0.0001134908,0.0009359239],"genre_scores_gemma":[0.8834931,0.002450807,0.1109174,0.0001020043,0.00001650575,0.0004795261,0.0006529281,0.00009599998,0.001791675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001494318,"threshold_uncertainty_score":0.004476666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03578639854304837,"score_gpt":0.3105124048368035,"score_spread":0.2747260062937552,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}