{"id":"W2042227544","doi":"10.1016/j.orthres.2005.01.020","title":"The effects of short‐term load duration on anabolic and catabolic gene expression in the rat tail intervertebral disc","year":2005,"lang":"en","type":"article","venue":"Journal of Orthopaedic Research®","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; National Institute for Health and Care Research","keywords":"Aggrecan; Intervertebral disc; Anabolism; Chemistry; In vivo; Context (archaeology); Messenger RNA; Annulus (botany); Matrix metalloproteinase; Internal medicine; Endocrinology; Anatomy; Biology; Pathology; Medicine; Biochemistry; Gene; Osteoarthritis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002735309,0.0001295914,0.0003295185,0.0003121813,0.000128675,0.00004167259,0.0002967526,0.00008553399,0.00002940195],"category_scores_gemma":[0.001834357,0.00005980159,0.0001751565,0.0003048124,0.0003047543,0.0002374881,0.00009667548,0.0008725377,0.000006631062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008814734,"about_ca_system_score_gemma":0.0001604484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001755396,"about_ca_topic_score_gemma":0.00009066176,"domain_scores_codex":[0.9972036,0.0006479257,0.0006783303,0.0001546725,0.0009848509,0.000330648],"domain_scores_gemma":[0.9988423,0.0002122526,0.0001862614,0.0003244701,0.0002998141,0.0001348972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001396117,0.001026002,0.0783104,0.0003722464,0.0001055272,0.001041109,0.004981165,0.000005995897,0.6090472,0.0003709834,0.02669622,0.276647],"study_design_scores_gemma":[0.0032038,0.004359686,0.9024342,0.001032698,0.0000471232,0.0007229095,0.0007449608,0.0001902582,0.08472562,0.000112983,0.002330563,0.00009524648],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885595,0.005687925,0.00005709096,0.004674328,0.0001912678,0.0003639902,0.00000144721,0.000003254285,0.0004612287],"genre_scores_gemma":[0.9959437,0.002874566,0.0001003664,0.0003138865,0.0005332999,0.00001568422,0.00000295205,0.00001302815,0.0002025794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8241237,"threshold_uncertainty_score":0.3790791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03340316332938798,"score_gpt":0.3619408107650577,"score_spread":0.3285376474356697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}