{"id":"W2042246675","doi":"10.1371/journal.pone.0077612","title":"Glycolytic Metabolites Are Critical Modulators of Oocyte Maturation and Viability","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Oocyte; Glycolysis; Biology; Xenopus; Cell biology; Human fertilization; Glyceraldehyde 3-phosphate dehydrogenase; Proteome; Phosphoenolpyruvate carboxykinase; Biochemistry; Gene expression; Enzyme; Embryo; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002012884,0.0003316872,0.0002703381,0.0002821338,0.0002184633,0.0005279933,0.0001391442,0.0003098217,0.001119191],"category_scores_gemma":[0.0002895791,0.0001703676,0.0001864112,0.0002221807,0.0002000016,0.0004013019,0.0002673816,0.0003638276,0.0001593051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003393272,"about_ca_system_score_gemma":0.0002246487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003309109,"about_ca_topic_score_gemma":0.0004866869,"domain_scores_codex":[0.9998429,0.00003080777,0.00001252443,0.00004051172,0.00003908538,0.00003411758],"domain_scores_gemma":[0.9997811,0.00003820923,0.0000871997,0.00001115138,0.0000386174,0.00004369969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003397626,0.0000185075,0.001471479,0.0001279727,0.00001281236,0.0001004063,0.00002721108,0.0000723847,0.9921748,0.0003134306,0.00006751289,0.005273625],"study_design_scores_gemma":[0.0000286931,0.0005707543,0.06133389,0.00003194576,0.0000555593,0.0004378317,0.0001099013,0.0005543337,0.9271175,0.0006095159,0.009130283,0.00001970101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9295534,0.05671941,0.006988868,0.0007641299,0.0001615108,0.00008212813,0.0009796672,0.0001516049,0.004599238],"genre_scores_gemma":[0.9869338,0.008334388,0.002424895,0.00009941716,0.000041463,0.00003207871,0.0003719695,0.00001936339,0.001742649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001119191,"threshold_uncertainty_score":0.003744066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03811414367608086,"score_gpt":0.2592921005206881,"score_spread":0.2211779568446073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}