{"id":"W2042270162","doi":"10.1016/j.fsi.2013.09.035","title":"Transcriptional regulation of teleost Aicda genes. Part 1 – Suppressors of promiscuous promoters","year":2013,"lang":"en","type":"article","venue":"Fish & Shellfish Immunology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"U.S. Department of Agriculture","keywords":"Biology; Activation-induced (cytidine) deaminase; Enhancer; Promoter; Zebrafish; Reporter gene; Regulatory sequence; Chloramphenicol acetyltransferase; Gene; Cytidine deaminase; Transcription factor; Genetics; Molecular biology; Cell biology; Gene expression; Somatic hypermutation; B cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001001457,0.0001689033,0.0002650533,0.00007389323,0.00003619109,0.00001023818,0.0003002777,0.0002670055,0.0006097385],"category_scores_gemma":[0.00003960973,0.0001638887,0.0001460957,0.00008194834,0.0002535768,0.00001523196,0.00007055878,0.00009299519,0.00002477658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001004398,"about_ca_system_score_gemma":0.00007457755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001224236,"about_ca_topic_score_gemma":0.00003787394,"domain_scores_codex":[0.9987506,0.00008404709,0.0004587609,0.0003227393,0.0001247645,0.0002590786],"domain_scores_gemma":[0.9990529,0.00001140562,0.000197658,0.0004141045,0.0002853182,0.00003862563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001221508,0.000133364,0.002595956,0.00003541189,0.0001590007,6.076833e-7,0.00008646131,0.00002917257,0.9855136,0.00004023178,0.007109003,0.004175038],"study_design_scores_gemma":[0.0006588708,0.00072373,0.07523672,0.00003114118,0.00002745336,0.00002417945,0.00008913442,0.00003458748,0.902669,0.0001670703,0.02015891,0.0001791926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969773,0.0008829253,0.000113065,0.0003516147,0.000340196,0.0003582253,0.00007859401,0.00001076008,0.0008873261],"genre_scores_gemma":[0.9970637,0.0005301088,0.0002990676,0.0001290092,0.00009311792,0.00006717126,0.0004442738,0.00002059487,0.00135297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08284459,"threshold_uncertainty_score":0.6683186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00786198003239335,"score_gpt":0.1977693990224245,"score_spread":0.1899074189900311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}