{"id":"W2042317364","doi":"10.1289/ehp.1205963","title":"MicroRNA Expression in Response to Controlled Exposure to Diesel Exhaust: Attenuation by the Antioxidant <i>N</i> -Acetylcysteine in a Randomized Crossover Study","year":2013,"lang":"en","type":"article","venue":"Environmental Health Perspectives","topic":"Air Quality and Health Impacts","field":"Environmental Science","cited_by":102,"is_retracted":false,"has_abstract":true,"ca_institutions":"Prevention of Organ Failure; Vancouver General Hospital; St. Paul's Hospital; Vancouver Coastal Health Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; Mochida Memorial Foundation for Medical and Pharmaceutical Research","keywords":"GCLC; Acetylcysteine; Oxidative stress; Antioxidant; Chemistry; Pharmacology; Molecular biology; Immunology; Medicine; Biochemistry; Glutathione; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002131045,0.001241181,0.003278104,0.0003635925,0.0006166744,0.0009502831,0.0007355795,0.001514307,0.00308006],"category_scores_gemma":[0.001726986,0.0008118852,0.001397402,0.000402751,0.00127508,0.0006768284,0.0004660357,0.001413493,0.0005208332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006055145,"about_ca_system_score_gemma":0.00106281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007313298,"about_ca_topic_score_gemma":0.001007503,"domain_scores_codex":[0.9986305,0.0004964217,0.0001493257,0.0004069433,0.0001386445,0.0001781117],"domain_scores_gemma":[0.9983904,0.0002676454,0.0004460879,0.000241015,0.0002124643,0.0004423488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9559242,0.01787352,0.001104984,0.0002539199,0.0005271671,0.00002233246,0.00004899453,0.0000907744,0.02048193,0.00002616583,0.0001370819,0.003508911],"study_design_scores_gemma":[0.4692005,0.5067278,0.01313904,0.00002301695,0.001444912,0.00004573779,0.0000642605,0.0004420542,0.00760047,0.0001022686,0.001162091,0.00004798572],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948172,0.0006023254,0.0008226015,0.00007452427,0.0002881548,0.002703719,0.0003993123,0.00004718565,0.0002449469],"genre_scores_gemma":[0.985863,0.000680041,0.002936853,0.0003263062,0.0003400165,0.007487493,0.0006069107,0.00003094567,0.00172833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003278104,"threshold_uncertainty_score":0.01127017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01321717130175026,"score_gpt":0.3010169625133676,"score_spread":0.2877997912116174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}