{"id":"W2042349538","doi":"10.1139/v02-077","title":"On expanding the repertoire of glycosynthases: Mutant β-galactosidases forming β-(1,6)-linkages","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Glycosidic bond; Glycosyl; Glycosyl donor; Stereochemistry; Glycoside hydrolase; Enzyme; Yield (engineering); Mutant; Oligosaccharide; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003314587,0.0009324739,0.0003862278,0.0004540098,0.0002541535,0.0006148231,0.0005703369,0.0004085002,0.001849386],"category_scores_gemma":[0.000220074,0.0001971664,0.0002457699,0.0004138095,0.0006745736,0.0008307806,0.0004979757,0.0008245057,0.001150841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004051989,"about_ca_system_score_gemma":0.0002955731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005279938,"about_ca_topic_score_gemma":0.0008822503,"domain_scores_codex":[0.9998009,0.00002314866,0.00001739077,0.00004539495,0.00008379739,0.00002940819],"domain_scores_gemma":[0.9998399,0.00003747976,0.00004156655,0.00003337463,0.00002130408,0.00002630741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001270285,0.00004243248,0.0002383905,0.0001302679,0.000007118105,0.0001481853,0.00004580857,0.0003722247,0.9647514,0.003437778,0.0003070734,0.03039219],"study_design_scores_gemma":[0.00001647869,0.0002837083,0.0005078749,0.00001667236,0.00001956661,0.0004745901,0.00001607395,0.0007202917,0.9814484,0.00052006,0.01596384,0.00001245871],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8634537,0.01953717,0.08551404,0.001880461,0.0002791542,0.0003055802,0.0007034823,0.001657232,0.02666922],"genre_scores_gemma":[0.8571609,0.04156514,0.07976174,0.0006838735,0.0001402387,0.0001459639,0.001260684,0.000328395,0.01895316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001849386,"threshold_uncertainty_score":0.006186783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0178603237612992,"score_gpt":0.2098248898893739,"score_spread":0.1919645661280747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}